垂体转移癌的诊断及治疗  

Diagnosis and Treatment of Pituitary Metastatic Carcinoma

作　　者：刘春晖[1] 毛更生[1] 

机构地区：[1]武警总医院神经血管外科,北京100039

出　　处：《长春中医药大学学报》2013年第5期919-920,共2页Journal of Changchun University of Chinese Medicine

摘　　要：目的探讨垂体转移癌的临床特点,提高对垂体转移癌的认识和诊治水平。方法对11例经病理证实的垂体转移癌患者的临床资料进行分析,讨论垂体转移癌的临床特点、诊断和治疗。结果 11例患者有4例来源于乳腺,2例来源于肺部,2例来源于胃肠道,1例来源于前列腺,1例来源于肾脏,1例来源于甲状腺,其中视神经损害4例,尿崩5例,垂体功能低下8例,眼外肌麻痹3例,生存期（83~490）d,平均（242±25）d。结论垂体转移癌是颅内罕见病变,多来源于乳腺和肺部,以视神经损害、尿崩、垂体功能低下和眼外肌麻痹为首发症状,预后较差。Objective To explore the clinical feature of pituitary metastatic carcinoma and improve the diagnose and treatment level of pituitary metastatic carcinoma.Methods We analysed the clinical data of eleven pituitary metastatic carcinoma patients who was confirmed by pathology and discussed the clinical feature,diagnose and treatment of pituitary metastatic carcinoma.Results There are four patients derived from breast,two patients derived from lungs,two patients derived from gastrointestinal tract,one patient derived from prostate glands,one patient derived from kidney,one patient derived from thyroid gland,and there are four patients manifested The optic nerve damage,five patients manifested diabetes insipidus,eight patients manifested hypopituitarism,three patients manifested Extraocular myoparalysis.The lifetime is（83 ~ 490） d,the mean is（242 ± 25）d.Conclusions Pituitary metastatic carcinoma is a rare lesion in intracalvarium,most come from mammary gland and lungs,manifested with urinary collapse,hypopsia,hypopituitarism and paralysis of extraocular muscles as first signs.

关 键 词：垂体 转移癌 综合治疗 

分 类 号：R273[医药卫生—中西医结合]