α-氰基苯烯酸正辛酯靶血管栓塞治疗难治性大咯血  

Target-vessel embolization with α-benzene acid ester for the treatment of intractable massive haemoptysis

作　　者：张宏文[1] 王小宜[1] 廖伟华[1] 邓小军[2] 邓梨平[2] 段诗姣[2] 肖燕[2] 谢卫华[2] 

机构地区：[1]长沙中南大学湘雅医院放射科,410008 [2]湖南衡阳南华大学附属南华医院血管介入科

出　　处：《介入放射学杂志》2013年第11期900-903,共4页Journal of Interventional Radiology

摘　　要：目的 探讨用永久性栓塞剂α-氰基苯烯酸正辛酯（TH胶）经支气管动脉栓塞治疗大咯血的临床疗效。方法 2009年1月—2012 年5月对42例内科治疗无效的大咯血患者进行支气管动脉栓塞治疗。42 例中，支气管扩张30例，支气管肺癌3例，肺结核合并支气管扩张6例，不明原因支气管病变3例，均采用TH胶栓塞。所有病例随访 12个月以上。结果 所有患者均成功实施支气管动脉栓塞，42 例即刻效果均为咯血停止，有效率 100％。术后3个月内复发1例，3 ～ 12个月内复发3例，12个月以上复发4例。复发患者血管造影均为遗漏血管所致，所有患者栓塞后均未出现严重并发症，术后平均住院时间为 9 d。结论 采用TH胶治疗难治性大咯血是一种安全、有效、复发率低的方法。Objective To evaluate the clinical efficacy and safety of bronchial artery embolization （BAE） by using permanent embolic material a-benzene acid ester （TH glue） in treating refractory massive hemoptysis. Methods During the period from Jan. 2009 to May 2012 a total of forty- two patients with refractory massive hemoptysis who had failed to respond to medical management received BAE. The causative diseases included bronchiectasis （n = 30）, bronchogenic carcinoma （n = 3）, bronchiectasis associated with tuberculosis （n = 6） and bronchial lesion of unknown reason （n = 3）. Embolization with TH glue was performed in all patients. All patients were followed up for more than 12 months. Results BAE was successfully accomplished in all patients. Immediate cessation of hemoptysis was obtained in all patients, with a success rate of 100%. Postoperative recurrence within 3 months was seen in one case, within 3 - 12 months in 3 cases and over 12 months in 4 cases. No serious complications occurred, and the mean postoperative hospitalization time of the patients was 9 days. Conclusion For refractory massive hemoptysis, BAE with TH glue is a safe and effective treatment with lower recurrence rate.

关 键 词：咯血 血管内栓塞 介入治疗 α-氰基苯烯酸正辛酯 

分 类 号：R562.22[医药卫生—呼吸系统]