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机构地区:[1]Stowers Institute for Medical Research, 1000East 50th Street, Kansas City, MO 64110, USA
出 处:《Cell Research》2013年第10期1153-1154,共2页细胞研究(英文版)
摘 要:How cells ensure that productive transcription from divergent pro- moters is limited to the downstream protein-coding region is an important question in the transcription field. A recent study in Nature proposed an answer by revealing that the up- stream antisense transcripts undergo early termination through the polyad- enylation signal-dependent pathway, and the downstream sense transcripts are protected from premature cleav- age by U1 small nuclear ribonucleo- protein (snRNP).
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