清远市钩端螺旋体病血清学监测结果分析  

Serological surveillance of leptospirosis in Qingyuan

作　　者：邓远玲 孙小康[1] 陈文青[1] 罗文玲[1] 李桂杭[1] 朱劲涛[1] 

机构地区：[1]清远市疾病预防控制中心,广东清远511515

出　　处：《中国卫生检验杂志》2013年第12期2643-2646,共4页Chinese Journal of Health Laboratory Technology

摘　　要：目的了解清远市钩端螺旋体病抗体(钩体抗体)在健康人群及宿主动物血清中的水平及菌群分布情况,为制定钩端螺旋体病防治措施提供科学依据。方法采用显微镜凝集试验(MAT)对采集的健康人血清和动物血清进行检测。结果 2007年-2011年采集健康人血清、宿主动物中鼠类、鸭、犬血清,钩体抗体平均阳性率分别为16.53%、23.95%、4.98%、12.15%;血清菌群分布:健康人群以秋季热为主、鼠类以拜伦群为主、鸭以七日热群为主、犬以秋季热群为主,鼠密度为8.66%,鼠种以褐家鼠为主。结论清远市健康人群及鼠类血清钩体抗体水平有所下降;监测的三种宿主动物中,鼠类血清钩体抗体阳性率最高,鼠类仍然是传播钩体病的主要传染源和重点监测对象;清远市鼠密度高,存在钩体病流行的风险。Objective To understand the anti - leptospira antibody level and bacterial distribution in the serum of healthy people and host animals, so as to provide scientific basis for prevention and control of leptospirosis. Methods Serum samples were collected from healthy people and host animals, and tested for antibodies to 15 leptospira serovars using the microscopic agglutination test（MAT）. Results From 2007 to 2011, serum samples were collected from healthy people and host animals, such as the rats, ducks and dogs. The average positive rates of anti -leptospira antibody were 16.53%, 23.95%, 4.98%, 12.15%, respectively. The main serotype was Leptospira autumnalis in human beings and dogs, which was Leptospira ballom in rats and Leptospira Hebdomadis in ducks. The rat density was 8.66% and the dominant species was rattus norvegicus. Conclusion In the three host animals, the positive rate of rat serum was the highest, indicating the rats were still the main source and key monitoring object for leptospirosis epidemic. The rat density is high, so there is still a risk of leptospirosis epidemic.

关 键 词：钩端螺旋体病 血清学 监测 分析 

分 类 号：R514.4[医药卫生—内科学]