GC-MS检测新型策划毒品K3  

Identification of the New Type Drug K3 by GC-MS

作　　者：李茂盛[1] 郑水庆[1] 陈永生[1] 刘琦[1] 张润生[1] 

机构地区：[1]上海市公安局物证鉴定中心,上海市毒品检验中心,上海市现场物证重点实验室,省部共建国家重点实验室培育基地

出　　处：《中国司法鉴定》2013年第5期20-22,27,共4页Chinese Journal of Forensic Sciences

基　　金：上海市科委科技攻关项目资助(10231204500)

摘　　要：目的基于气相色谱-质谱(GC-MS)检测结合特殊质谱库信息检索建立新型策划毒品的鉴定方法。方法未知样品用甲醇超声溶解,吸取上清液采用气相色谱-质谱(GC-MS)联用仪检测。结果测得A组分(t R=19.47min)的质谱特征碎片峰(m/z)信息为215.1(基峰)、144.9、294.1、337.1和365.1,B组分(tR=23.29min)的质谱特征碎片峰(m/z)信息为359.1(基峰)、127.1、144.0、155.0、232.1、284.1和342.0。经美国缉毒署毒品分析谱库检索获得的信息资料,鉴定为新型策划毒品"K3",其主要组分为"AKB48"和"AM2201",此类化合物具有大麻类似精神活性,归属合成大麻素。结论本方法可用于新型策划毒品组分的鉴定。Objective To establish a gas chromatography-mass spectrometry （GC-MS） method with special mass spectra library searching for the identification of the new-type drugs. Method The sample extraction was performed with methanol in ultrason- ic bath. And the supernatant was injected into GC-MS system. Results Component A （tR = 19.47min） has characteristic frag- ment ion peaks at m/z 215.1 （base peak）, 144.9, 294. l, 337.1 and 365.1. Component B （tR =23.29min） has characteristic fragment ion peaks at m/z 359.1 （base peak）, 127.1, 144.0, 155.0, 232.1, 284.1 and 342.0. According to the information searched from U.S. Drug Enforcement Administration mass spectra library, this drug is identified as new-type drug ＂K3＂. Its main components are ＂AKB48＂ and ＂AM2201＂. The drug has similar psychoactive activity to marijuana and belongs to synthet- ic cannabinoids. Conclusion The method can be used for identifvin~ comoonents of the new-tvoe dru^s.

关 键 词：法庭科学 新型策划毒品 K3 合成大麻素 AKB48 AM2201 GC-MS 

分 类 号：D918.93[政治法律—法学]