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机构地区:[1]中国中医科学院广安门医院,北京100053 [2]中国中医科学院中药研究所,北京100700
出 处:《中国实验方剂学杂志》2013年第20期325-329,共5页Chinese Journal of Experimental Traditional Medical Formulae
基 金:中国中医科学院自主选题项目(2011xycz-02)
摘 要:利用固体分散技术新原理制备的中药滴丸剂现已成为一种有发展前途的中药新剂型。该剂型以中医、中药学为理论基础,辅以现代剂型新技术,并与其他制剂技术相结合,经过精制、富集有效成分或有效部位制备而成,其成分明确,质量易于控制、提高药物生物利用度。随着近年来滴丸相关辅料和制备工艺研究的不断深入和发展,在临床应用中逐渐显示出其优势,并表现出其他传统中药剂型所不具备的一些优点。与传统中药制剂相比避免了传统中药生物利用度低、服用不方便、起效慢的缺点,同时发扬了传统中药毒副作用小、安全性好、不良反应少等优点。更接近中药现代化要求。中药滴丸剂这一优良剂型得到了更为广泛的应用。Based on the principle of the solid dispersion prepared traditional Chinese medicine pills agent has now become a promising new formulations of traditional Chinese medicine.The formulation based on the theory of Chinese medicine and Chinese pharmacy,Supplemented by modem forms of technology and other preparation techniques,refined and enriched preparation can be obtained from the active ingredients or effective parts.Their composition is clear,the mass is easy to control and improve the bioavailability of a drug.Recent years,with dripping pills accessories and preparation deepening of the research and development,clinical applications gradually shows its advantages of traditional Chinese medicine formulations than others do not have.Compared with the traditional Chinese medicine,dripping pills can avoid the low bioavailability and functional shortcomings of slow,meanwhile carry forward the ascendancies of traditional Chinese medicine,such as low side effects,security and fewer adverse reactions,etc.Chinese medicine pills agent has been more widely used,which be much closer to the requirements of the modernization of traditional Chinese medicine.
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