高效液相色谱-串联质谱法测定食品包装材料中10种增塑剂  

Determination of 10 Plasticizers in Food Packaging Materials by Ultraperformance Liquid Chromatography Tandem Mass Spectrometry

作　　者：王宽强 张旭龙[2] 马玲[1] 刘银[1] 彭秧[1] 

机构地区：[1]新疆大学化学化工学院,新疆乌鲁木齐830046 [2]新疆出入境检验检疫局,新疆乌鲁木齐830063

出　　处：《分析科学学报》2013年第5期660-664,共5页Journal of Analytical Science

基　　金：国家自然科学基金(No.201147005);国家质检总局项目

摘　　要：建立了超声萃取,高效液相色谱-串联质谱法测定食品包装材料中10种增塑剂的方法。以甲醇和0.1%的甲酸水溶液为流动相、梯度洗脱、正离子电离模式(ESI+)、多反应监测扫描(MRM)对10种增塑剂进行定性与定量分析。结果表明,10种增塑剂都有较好的线性关系(r>0.99),定量限(S/N=10)在3.0～0.5μg/L。该方法的回收率为71.63%～118.33%,相对标准偏差为0.15%～17.68%(n=6)。实验表明该方法检测速度快,灵敏度高,适合于食品包装材料中增塑剂的检测。Ultrasonic extraction-Ultraperformance liquid chromatography tandem mass spectrometry （UPLC-LC/LC） was established for the simultaneous determination of 10 plasticizers in food Packaging materials. Under the mode of positive elect-spray ionization （ESI＋）, multi-reaction monitoring （MRM） was adopted for qualitative and quantitative analysis of 10 plasticizers,using a mobile phase of methanol and 0.1% formic acid/water solution in the gradient mode. The results showed that 10 plasticizers have good linear relationships,and correlation coefficients（r） were all more than 0.99 with the quantification limits between 3.0-0.5 μg/L（S/N= 10）. The average recoveries of 10 plasticizers at three spiked levels ranged from 71.63%-118.33% with relative standard deviations of 0. 15%-17.68%. The method was rapid,highly sensitive and was suitable for the determination of 10 plasticizers in food packaging materials.

关 键 词：增塑剂 高效液相色谱-质谱 食品包装材料 

分 类 号：O657.63[理学—分析化学]