健康人24小时QT变异度  

QT variability during 24 hours in healthy subjects

作　　者：胡大一[1] 李瑞杰[1] 郭成军[1] 杨新春[1] 郭晋萍[1] 

机构地区：[1]首都医科大学心血管病研究所,北京红十字朝阳医院心脏中心,100020

出　　处：《临床心电学杂志》2000年第4期196-198,共3页Journal of Clinical Electrocardiology

摘　　要：目的　描述健康人的 2 4小时 QT变异度。方法　 5 8例健康人在日常生活状态下接受 2 4小时 Holter监测 ,计算机自动计算每小时 QT间期均数 (QTm )和标准差 ,后者用以表示相应时间段的 QT变异度 (QTv)。以频域法同步分析心率变异性。结果　夜间迷走神经活性增高时 QTm值大 (最大值为 371±2 1m s,于 0 3:0 0 - 0 4:0 0时间段 )、QTv值小 (最小值为 5 .8± 0 .7m s,于 0 1:0 0 - 0 2 :0 0时间段 ) ,白天交感神经活性增高时 QTm值小 (最小值为 30 5± 12 m s,于 11:0 0 - 12 :0 0时间段 )、QTv值大 ,主要以上午最大并于 0 7:0 0 - 0 8:0 0达 2 4小时最高值 (15 .9± 2 .6 ms)。结论　健康人的 2 4小时 QT变异度与自主神经活性状态有关 ,呈昼夜节律性变化。Objective To Study QT variability(QTv)during 24 hours in healthy subjects.Methods 58 healthy subjects underwent 24 hours Holter monitoring in normal life style.The mean of QT intervals(QTm) and the standard deviation of QT intervals (QTv) were calculated and heart rate variability were analyzed simultaneously by computer for every hour during 24 hours.Results The QTm is shorter and the QTv is larger during the day or the dominance of sympathetic activity,especially in the morning,than during at night or the dominance of parasympathetic activity.The largest value and the smallest value of QTm during 24 hours are 371±21ms(03:00-04:00) and 305±12ms(11:00-12:00),while the largest value and the smallest value of QTv during 24 hours are 15.9±2.6ms(07:-08:00) and 5.8±0.7 ms(01:00-22:00),respectively.Conclusion The QT variability has a regular pattern during the day and night in healthy subjects.This pattern is related to the autonomic nervous activity.

关 键 词：健康人 QT间期 心率变异性 动态心电图 

分 类 号：R540.41[医药卫生—心血管疾病]