大鼠心血管系统内血液压强分布的研究  

Study on distribution of blood pressure in the cardiovascular system of rat

作　　者：张秋实[1] 张游[1] 李玉明 张诚 

机构地区：[1]承德医学院医用物理教研室 [2]承德医学院低温生理研究室,河北承德067000

出　　处：《中国医学物理学杂志》2000年第4期243-244,246,共3页Chinese Journal of Medical Physics

基　　金：国家自然科学基金资助项目(3870229)

摘　　要：目的：研究大鼠心血管内血液压强的分布。方法：实验动物采用Wistar大鼠n ＝15 。在封闭条件下用4导生理记录仪记录大鼠心血管系统内各部位的血液压强。本方法较传统的液体检压计法更为精确。结果：本实验得出大鼠心血管系统内血液压强的分布及其特点为：（1）左室收缩压（LVSP ）为（145．00±15．61） mmHg 主动脉收缩压（ASP ）为（126．87±11．16） mmHg 即LVSP高于ASP 右室收缩压RVSP 为（35．04±3．95） mmHg 肺动脉收缩压PASP 为（27．03±3．46） mmHg 即RVSP高于PASP。上述血液压强的分布与人类有所差异。（2）大鼠血管系统各部位压强（包括ASP、ADP、MAP、PASP、PADP、MPAP、CVP、WP ）的数值大小和变化范围大致与人类相同。结论：（1）大鼠的LVSP高于ASP，RVSP高于PASP ，此血压分布不同于人类。（2）与人类相比，大鼠的LVSP和RVSP较高，而其血管系统各部位的血液压强的大小和分布情况大致与人类相同。： Purpose To study the distribution of blood pressure in the cardiovascular system of rat．Method The experimental animal is Wistar rat n＝15 ． The blood pressure in different parts of the cardiovascular system were recorded with a 4－channel polygraph system under closing condition． This method is more exact than that of manometer． Results Our experiments demonstrated the following distribution of blood pressure in the cardiovascular system of rat． 1 The left ventricular systolic pressureLVSP was 145．00±15．16 mmHg and the aortal systolic pressureASP was 126．87±11．16 mmHg． The LVSP was higher than ASP ． The right ventricular systolic pressureRVSP was 35．04±3．95 mmHg and the pulmonary arterial systolic pressurePASP was 27．03±3．46 mmHg． The RVSP was higher than PASP． This distribution of blood pressure was different with human． 2 On Value and range the blood pressure in vascular system of rat including ASP、ADP、MAP、PASP、PADP、MPAP、CVP、WP were close to human． Conclusion 1 The LVSP was higher than ASP and the RVSP was higher than PASP． This distribution of blood pressure of rat was different with human． 2 The LVSP and RVSP of rat were higher when compared with human and the blood pressure distribution of other parts in the vascular system of rat was close to human．

关 键 词：大鼠 心血管系统 血液压强的分布 

分 类 号：R331.1[医药卫生—人体生理学]