固体酸催化合成2-乙酰噻吩  

Synthesis of 2-Acethyl Thiophene Catalyzed by Solid Acid

作　　者：王丽[1] 朱贤江[1] 蔡可迎[1] 

机构地区：[1]徐州工程学院化学化工学院,江苏徐州221018

出　　处：《广东化工》2013年第19期26-27,共2页Guangdong Chemical Industry

基　　金：国家级大学生实践创新训练计划项目(项目编号:GCX2012010);徐州工程学院大学生创新创业基金项目(项目编号:201317)

摘　　要：制备了磷酸/活性白土、FeCl3/活性白土、Fe(III)树脂、SO42-/Fe2O3等固体酸催化剂,并考察了其对噻吩与乙酸酐反应合成2-乙酰噻吩的催化性能。结果表明,磷酸/活性白土的催化效果较好。在适宜的反应条件下,以磷酸/活性白土为催化剂,合成2-乙酰噻吩的收率达到90%,选择性高于99%。催化剂重复使用4次后,活性有一定的下降。The solid acid catalysts, such as H3PO4/actived clay, FeCl3/actived clay, Fe（Ⅲ） resin and SO42-/Fe2O3 were prepared for the synthesis of 2-acethyl thiophene from thiophene and acetic anhydride, and their catalytic performance was investigated. The results show that H3PO4/actived clay has a good performance. H3PO4/actived clay as catalyst, the yield and selectivity of 2-acetylthiophene can reach 90 % and 99 % respectively under the optimum conditions. The catalytic activity decreased slightly after 4 runs.

关 键 词：2-乙酰噻吩 合成 固体酸 

分 类 号：TQ251.2[化学工程—有机化工]