2011～2012年专项整治前后常德市第一人民医院住院患者抗菌药物应用分析  

Analysis on Antibiotics Application for Inpatients before and after the Special Rectification on Antibiotic Use from 2011 to 2012in First People′s Hospital of changde city

作　　者：曾玲[1] 王珍珊[1] 沈毅[1] 程钢[1] 周述香[1] 

机构地区：[1]湖南省常德市第一人民医院,常德415003

出　　处：《中国药事》2013年第11期1221-1224,共4页Chinese Pharmaceutical Affairs

摘　　要：目的分析比较专项整治前后常德市第一人民医院住院患者抗菌药物使用情况,评价整治活动效果。方法收集专项整治前(2011年度)、后(2012年度)抗菌药物使用数据,统计抗菌药物销售情况、使用强度、用药频度及日均费用。结果专项整治后我院住院患者抗菌药物年销售金额、占药品总收入比及抗菌药物使用强度大幅下降,整治活动行之有效。头孢菌素和含酶抑制剂类药物连续2年列DDDs前列,2012年氟喹诺酮类、碳青霉烯类、糖肽类DDDs总量和比例都有所上升。头孢美唑注射剂DDDs连续2年排名第一。结论专项整治活动后我院住院患者抗菌药物使用日趋合理,抗菌药物使用强度、频率都得到有效控制,但仍存在用药集中、起点高、广谱抗菌药物使用频率高等问题,需进一步加强管理和监督。Objective To compare and analyze antibiotics application for inpatients before and after the special rectification on antibiotic use and to investigate the effect of rectification measures. Methods The use of antibiotics before （in 2011） and after （in 2012） the special rectification was statistically analyzed, including consumption sum, antibiotics use density （AUD）, defined daily doses （DDDs） and daily drug cost （DDC）. Results Remarkable decrease of antibiotic agents cost, ratio of consumption sum to total drug incomes and AUD demonstrated the rectification measures were effective and feasible. Among all antibiotics, DDDs of cephalosporin and beta-lactamase inhibitor remained top 2 over the two years. In 2012, the DDD amounts and the constituent ratios of fluroquinolone, carbapenem and glycopeptide all increased. The DDDs of Cefmetazole Injection ranked top 1 over the two years. Conclusion After the special rectification on antibiotic use, the use of antibiotic agents were becoming more reasonable, the use frequency and density of antibiotics was effectively controlled, but there was still many problems, such as over-centralized drug use, high starting of drug choice and high use frequency of broad spectrum antibiotics. Supervision and management should be further strengthened.

关 键 词：抗菌药物 专项整治 应用分析 

分 类 号：R969.3[医药卫生—药理学]