PET-CT检查注射药物时采用不同分组方法所需^(18)F-FDG量的研究  

Study on the Required Theoretical Amounts of ^(18)F- FDG when Different Grouping Methods were Applied During PET-CT Examination.

作　　者：张红雨 张忠太[1] 李迎新[2] 徐树伟[1] 崔洁[1] 郭芳[1] 

机构地区：[1]山西省肿瘤医院PET/CT中心,太原030013 [2]中国医学科学院-中国协和医科大学生物医学工程研究所,天津300192

出　　处：《中国辐射卫生》2013年第5期537-539,共3页Chinese Journal of Radiological Health

摘　　要：目的为了寻找一种合适的分组方法,使得行PET-CT检查时,在不影响图像质量的前提下,可以节省放射性药物18F-FDG的量,节约成本,减少辐射。方法分别对12人次检查时采取A、B、C、D 4种不同的分组方法进行理论计算分析。结果方法 A(每组注射1人次,每组间隔20 min,共12组)需要18F-FDG的量最多,方法 D(每组注射4人次,每组间隔80 min,共3组)需要18F-FDG的量最少。方法 B(每组注射2人次,每组间隔40 min,共6组)、方法 C(每组注射3人次,每组间隔60 min,共4组)、方法 D分别比方法 A所需药物的量少了5.0%、9.4%、14.0%。结论 PET-CT检查时注射药物采用3人次一组的方式最为理想,其不影响图像质量和检查效果,而且还节省药物和减少对工作人员的辐射,因此建议采用该分组方法给受检者注射药物。Objective To explore one grouping method which can reduce the amount of radiopharmaceutical 18 F - FDG, when PET - CT examinations were performed without image losses of diagnostic utility. Methods 12 patients were divided into 12, 6, 4, 3 groups by method A, B, C, D. The required theoretical amounts of 18SF- FDG for every patient were calculated and analyzed. Results The experiments showed that the required theoretical amounts for method A （ 1 patient in each group, injection interval, 20 minutes） was at maximum, method D was at least. Compared with method A, the required theoretical amounts for method B （2 patients in each group, injection interval, 40 minutes）, C （3 patients in each group, in- jection interval, 60 minutes） , D （4 patients in each group, injection interval, 80 minutes） decreased 5.0%, 9.4% , 14.0%, respectively. Condusion The results showed that Method C is the best choice when PET - CT examinations were performed without image losses of diagnostic utility, and it can reduce the operating cost and operator radiation, so it was rec ommended in practical application.

关 键 词：18F—FDG PET—CT 放射性药物 

分 类 号：R144.1[医药卫生—公共卫生与预防医学]