PARTIAL CARBAMOYLATION OF CELLULOSE MICROSPHERES: A NEW METHOD TO PREPARE ADSORBENTS FOR LIQUID CHROMATOGRAPHY  

作　　者：Wei Chen Qin Bin 柏正武 周兴平 Xiao-lin Xie 

机构地区：[1]Key Lab for Large-Format Battery Materials and Systems,Ministry of Education,School of Chemistry and Chemical Engineering,Huazhong University of Science and Technology [2]Key Lab of Green Chemical Process,Ministry of Education,Hubei Key Laboratory of Novel Chemical Reactor and Green Chemical Technology,Wuhan Institute of Technology

出　　处：《Chinese Journal of Polymer Science》2013年第12期1725-1732,共8页高分子科学（英文版）

基　　金：the National Natural Science Foundation of China(Nos.50973086 and 51273073);Hubei Provincial Department of Education of China(Z 20081501)

摘　　要：Micron-sized cellulose microspheres were prepared through sol-gel method using NaOH/urea solution to dissolve cellulose, then cross-linked by 1,6-hexanylene diisocyanate （HDI）, toluene 2,4-diisocyanate （TDI） and 1,4-phenylene diisocyanate （PDI）, respectively. The reaction conditions for partial modification of the microspheres were studied. The degree of substitution （DS） in cellulose was controlled by adjusting the reaction conditions. HDI-crosslinked microspheres were partially modified with phenyl isocyanate to obtain chiral stationary phases （CSPs）. The CSPs of a lower degree of crosslinking （DC） showed better chiral recognition ability than those of a higher DC. Meanwhile the CSPs prepared by pre- modification exhibited better chiral recognition ability than those prepared by pre-crosslinking.Micron-sized cellulose microspheres were prepared through sol-gel method using NaOH/urea solution to dissolve cellulose, then cross-linked by 1,6-hexanylene diisocyanate （HDI）, toluene 2,4-diisocyanate （TDI） and 1,4-phenylene diisocyanate （PDI）, respectively. The reaction conditions for partial modification of the microspheres were studied. The degree of substitution （DS） in cellulose was controlled by adjusting the reaction conditions. HDI-crosslinked microspheres were partially modified with phenyl isocyanate to obtain chiral stationary phases （CSPs）. The CSPs of a lower degree of crosslinking （DC） showed better chiral recognition ability than those of a higher DC. Meanwhile the CSPs prepared by pre- modification exhibited better chiral recognition ability than those prepared by pre-crosslinking.

关 键 词：CELLULOSE MICROSPHERES FUNCTIONALIZATION Chiral stationary phase Chiral recognition. 

分 类 号：O647.3[理学—物理化学]