6%羟乙基淀粉急性高容量血液稀释后对老年脊柱手术患者血液动力学及凝血功能的影响  

Effect of 6% Hydroxyethyl Starch Acute Hypervolemic Hemodilution on Hemodynamics and Coagulation Function in Elderly Patients with Spine Operation

作　　者：欧阳胜[1] 

机构地区：[1]四川省内江市第一人民医院麻醉科,四川内江641000

出　　处：《临床医学工程》2013年第11期1411-1412,共2页Clinical Medicine & Engineering

摘　　要：目的探讨6%羟乙基淀粉急性高容量血液稀释对老年脊柱手术患者血液动力学及凝血功能的影响。方法回顾性分析我院收治的56例老年脊柱手术患者的临床资料,根据麻醉方式不同分为治疗组和对照组各28例,其中治疗组患者麻醉前采用6%羟乙基淀粉急性高容量血液稀释,对照组注入乳酸钠林格氏液,比较两组患者的血液动力学和凝血功能的变化。结果治疗组患者输液后MAP和CVP均较输液前升高,且CVP显著高于对照组,P<0.05,HR显著低于对照组,P<0.05;两组患者输液前后凝血功能指标PT、APTT、Fib均无显著性差异,P>0.05。结论采用6%羟乙基淀粉急性高容量血液稀释后行老年脊柱手术,有助于改善血液动力学,对凝血功能无抑制作用。Objective To investigate the effect of 6% hydroxyethyl starch acute hypervolemic hemodilution on hemodynamics and coagulation function in elderly patients with spine operation. Methods The clinical data of 56 elderly patients with spinal operation was taken for retrospective analysis. According to the different ways of anesthesia, they were divided into the treatment group and the control group, with 28 cases in each group. The treatment group was taken with 6% hydroxyethyl starch acute hypervolemic hemodilution, and the control group was taken with sodium lactate ringer＇s solution. The changes of hemodynamic and coagulation function were compared between two groups. Results The MAP and CVP increased in the treatment group after infusion compared with those before infusion, and CVP was significantly higher than that of the control group, P〈0.05, HR were significantly lower than that of the control group, P〈0.05. The blood coagulation indexes of PT, APTT and Fib showed no significant difference between two groups before and after infusion, P 〉0.05. Conclusions The use of 6% hydroxyethyl starch acute hypervolemic hemodilution in aged patients after spinal operation can help to improve hemodynamics, and there is no inhibitory effect on coagulation function.

关 键 词：6%羟乙基淀粉 急性高容量血液稀释 老年脊柱手术 血液动力学 凝血功能 

分 类 号：R614[医药卫生—麻醉学]