术后认知功能障碍的研究进展  

Research Progress in Postoperative Cognitive Dysfunction

作　　者：彭慧萍[1] 顾小萍[1] 

机构地区：[1]南京大学医学院附属鼓楼医院麻醉科,南京210008

出　　处：《医学综述》2013年第21期3843-3846,共4页Medical Recapitulate

基　　金：国家自然科学基金面上项目(81171047/H0903);江苏省卫生厅科技兴卫项目(RC2011006)

摘　　要：术后认知功能障碍(POCD)是老年患者术后常见的中枢神经系统并发症,表现为记忆力、注意力和计算能力的减退。POCD可致患者康复延迟、住院天数延长及医疗费用增加等,严重时甚至影响患者出院后的生活质量。尽管已有大量的临床及实验室研究,但对POCD的发病机制仍不清楚,因此只能从可能引起POCD的相关因素着手,提高对POCD危险因素的认识,在围术期对高危人群进行早期干预。Postoperative cognitive dysfunction （POCD） is a subtle impairment of memory, concentration, and speed of information processing. It is a frequent complication following surgery and mainly seen in the elderly. It can have a debilitating effect on patients＇ recovery and future prognosis, such as longer hospital stay and extra cost,or even dent of quality of life after discharge. The precise pathogenesis of POCD is remain unknown,though a large number of clinical and laboratorial research have been done. To decrease the inci- dence of POCD, good basic care demands identification of at-risk patients,awareness of common perioperative aggravating factors, and recognition of the disease states are needed.

关 键 词：术后认知功能障碍 危险因素 发病机制 

分 类 号：R614.1[医药卫生—麻醉学]