参芍口服液对冠状动脉介入治疗术后再狭窄的影响  

The Effect of Shenshao Oral Lotion to Restenosis after Percutaneous Coronary Intervention

作　　者：张琦[1] 刘晓堃[1] 李映雪 薛忠文[1] 刘晓明[1] 刘长青[1] 岳博成 陈超[1] 尚小明[1] 

机构地区：[1]唐山市工人医院心内科,河北省唐山市063000

出　　处：《中国动脉硬化杂志》2013年第10期903-906,共4页Chinese Journal of Arteriosclerosis

基　　金：河北省科技计划项目(11276103D-90)

摘　　要：目的观察参芍口服液对PCI术后患者血脂、血液流变学以及术后支架内再狭窄的影响。方法 PCI术后患者1 023例,随机分为常规服药组514例和参芍口服液组509例,常规服药组采用西医常规治疗,参芍口服液组在常规治疗基础上加用参芍口服液,对两组患者随访12个月。结果参芍口服液组患者血清TC、TG和LDLC均有下降,与用药前相比差异有统计学意义(P<0.05),LDLC与常规服药组同期相比差异有统计学意义(P<0.05)。两组患者血液流变学指标均有降低,且参芍口服液组各指标值较同期常规服药组降低更显著,差异均有统计学意义(均P<0.05)。支架植入血管段管腔内径净获得、管腔面积净获得均大于常规服药组(P<0.05)。结论参芍口服液对PCI术后再狭窄的预防有一定作用。Aim To observe the effect of Shenshao oral lotion to blood lipid,hemorrheology,and stent restenosis in patients after percutaneous coronary coronary intervention （PCI）. Methods 1 023 patients with coronary heart disease were recruited into our study. Patients were randomly divided into two groups： conventional therapy group and ShenShao oral lotion taking group. Results The level of LDLC in patients of Shenshao oral lotion group decreased lower than that in conventional group in the same period. The indices of blood rheology in patients of Shenshao oral lotion were decreased lower than that in conventional therapy group. The late stage inner loss of the ShenShao oral lotion group was less than the conventional medicine group （P〈0.05）. Conclusion Shenshao oral lotion could effectively prevent restenosis after PCI.

关 键 词：参芍口服液 中药 冠心病 介入治疗 再狭窄 

分 类 号：R5[医药卫生—内科学]