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作 者:戴启春[1] 胡粟[1] 刘运练[1] 高茜[1] 闻芳[1] 胡春洪[1]
出 处:《临床放射学杂志》2013年第11期1576-1579,共4页Journal of Clinical Radiology
摘 要:目的分析显微镜下多血管炎(MPA)肺损害的CT表现,提高对本病的认识。方法搜集28例经临床证实的MPA的临床表现及胸部CT影像资料,分析肺部各种影像学表现的出现频率及分布情况。结果肺部CT主要表现:(1)磨玻璃影及散在斑片状高密度影22例(78.57%),均累及两肺。(2)小叶间隔增厚13例(46.43%),以两中下肺胸膜下分布为主。(3)实变影8例(28.57%),其中2例实变内可见空洞形成。(4)血管支气管周围管壁增厚7例(25.0%)。(5)结节影6例(21.43%),结节直径从0.3~3cm不等。(6)蜂窝影3例(10.71%),以两下肺胸膜下为主。(7)牵拉性支气管扩张4例(14.29%),2例伴有支气管扭曲。(8)纤维索条影6例(21.43%),以两下肺为主。(9)肺气肿5例(17.86%)。(10)混杂密度影3例(10.71%)。结论MPA患者肺损害CT表现呈多样性,以间质性病变为主。对临床诊断肺纤维化患者,应想到本病的可能,及时检测抗中性粒细胞质抗体,在出现不可逆的肺纤维化之前及时治疗,提高患者的生活质量及生存率。Objective To investigate the CT manifestations of pulmonary involvement with microscopic polyangiitis. Methods Clinical data and chest CT images of 28 paitents with clinic confirmed MPA were collected, the frequency and distribution of pulmonary imaging performance were analyzed. Results CT findings included ground glass opacities (78. 57% ), interlobular septal thickening(46.43% ), consolidation(28.57% ), bronchial wall thickening( 25.0% ), nodules (21.43%), honeycomb lung( 10.71% ), bronchial dilatation( 14.29% ), linear opacities(21.43% ) and pulmonary em- physema( 17.86% ). Conclusion Although CT manifestations of patients diagnosed as MPA with pulmonary involvement are diversity, most of them have intersitial pulmonary disease. Patients with pulmonary fibrosis should be alert to MPA, ANCA should be detected timely, and patients should be treated before irreversible pulmonary fibrosis in order to improve the patientg quality of life and survival rate.
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