正交实验优选参杞强精胶囊提取工艺  

Optimization of Extraction Process for Preparing Shenqi Qiangjing Capsule by Orthogonal Design

作　　者：田元春[1] 马儒清[1] 韦水林[1] 宾彬[1] 

机构地区：[1]广西中医药大学第一附属医院药学部,南宁530023

出　　处：《医药导报》2013年第11期1497-1500,共4页Herald of Medicine

基　　金：广西壮族自治区卫生厅中医药医院制剂类课题(GZYZ-10-05);广西壮族自治区卫生厅中医药科技专项课题(GZYZ1101)

摘　　要：目的优选参杞强精胶囊的提取工艺。方法以出膏率、金丝桃苷含量和总多糖含量为指标,采用L9(34)正交实验考察提取时间、提取次数、加水量等因素的影响,优化最佳提取工艺。结果最佳提取工艺为药材加12倍量水,提取3次,每次1.5 h。结论该提取工艺合理、稳定、可行。Objective To optimize the extraction process for preparation of sheruli qiangfing capsule. Methods The extraction duration,extraction times, and water load were optimized by the L9 （34） orthogonal test, using the paste-forming rate, hyperin content and total polysaccharide content as indicators. Results The optimum extraction process was determined by using 12-fold volume of water, extracting for 1.5 hours for 3 times. Conclusion The extraction process is rational, stable and feasible.

关 键 词：参杞强精胶囊 金丝桃苷 提取工艺 正交设计 

分 类 号：R286.3[医药卫生—中药学] TQ460.1[医药卫生—中医学]