兰科药用植物见血青乙酸乙酯部位化学成分研究  

Study on Chemical Constituents from Ethyl Acetate Extract of Liparis nervosa

作　　者：赵颖[1] 胡少南[1] 王昌华[2] 郑一敏[1] 胥秀英[1] 

机构地区：[1]重庆理工大学药学与生物工程学院,重庆400054 [2]重庆市中药研究院,重庆400065

出　　处：《中国实验方剂学杂志》2013年第22期111-113,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：重庆市教委科学技术研究项目(KJ110802);重庆理工大学科研启动基金项目(2010ZD07)

摘　　要：目的：研究见血青乙酸乙酯部位化学成分.方法：利用硅胶柱色谱和Sephadex LH-20凝胶柱色谱分离手段,根据波谱数据和理化性质进行结构鉴定.结果：从见血青75％乙醇提取物的乙酸乙酯萃取部位中分离鉴定了7个化合物,分别为2,2-二甲基-8-（3-羟基异戊烷）苯并二氢吡喃-6-羧酸（1）,亚油酸（2）,α-菠甾醇葡萄糖苷（3）,单棕榈酸甘油酯（4）,芫花素（5）,芹菜素（6）,琥珀酸（7）.结论：化合物1为新的天然产物,化合物2～7均为首次从见血青中分离得到.Objective：To study the chemical constituents of the ethyl acetate extract of Liparis nervosa.Method：Chemical constituents were isolated by Column chromatography on Silica gel and Sephadex LH-20,their structures were identified by physicochemical characters and spectroscopic analysis or comparison with standard compounds.Result：Seven compounds were isolated and identified as 2,2-dimethyl-8（3-hydroxyisoamyl）chroman-6-carboxylic acid （1）,linoleic acid （2）,α-spinasterol glucoside （3）,glycerol monopalmitate （4）,genkwanin （5）,apigenin （6）,butane diacid （7）.Conclusion：Compounds 1 was a new natural product,2-7were isolated from L.nervosa for the first time.

关 键 词：见血青 化学成分 结构鉴定 

分 类 号：R284.1[医药卫生—中药学]