1～6月龄正常婴儿听性脑干反应检测结果分析  

Auditory Brainstem Responses of 1-6 Month Normal Infants

作　　者：郑周数[1] 陈淑飞[1] 邵小飞[1] 苏仁杰[2] 史波宁[1] 

机构地区：[1]宁波大学医学院附属医院听觉与平衡医学中心、宁波市儿童听力筛查诊断和治疗中心、宁波市听觉和平衡医学重点实验室,宁波315020 [2]宁波大学医学院

出　　处：《听力学及言语疾病杂志》2013年第6期593-595,共3页Journal of Audiology and Speech Pathology

摘　　要：目的探讨1～6月龄正常婴儿听性脑干反应（ABR）的变化规律，建立小婴儿ABR波I、III、V潜伏期及波间期正常参考值。方法对166例（269耳）1月龄、141例（226耳）2月龄、111例（177耳）3月龄、58例（96耳）4月龄、78例（121耳）5月龄和45例（76耳）6月龄正常婴儿进行短声（click）ABR测试，分析反应阈及各波潜伏期、波间期。结果1～6月龄正常婴儿ABR反应阈均值为16．18±5．35dBnHL，波V潜伏期均值9．03±0．49ms，各月龄组反应阈差异无统计学意义（P〉0．05）。在80dBnHL刺激声强度时，波I、III、V引出率均为100％，随着刺激声强的降低，以波V的稳定性最好，波I消失最快，各波潜伏期均延长，标准差增大，各波间期缩短。在同一刺激声强下，随着月龄的增长，波I潜伏期无明显变化，波III、V潜伏期和I—III、III—V、I—V波间期均有明显缩短。在4月龄前波III、V潜伏期和I—III、III—V、I—V波间期各月龄组间差异均有统计学意义（P〈0．05），4月龄后各月龄组间的差异无统计学意义（P〉0．05）。结论本组1～6月龄正常婴儿短声诱发听性脑干反应反应阈的正常值为16．18±5．35dBnHL；下丘以下听觉神经传导径路在出生后1～4月有较快的发育过程。Objective To investigate the characteristics of click--auditory brainstem response （ABR） in nor- mal infants of 1 to 6 months old, and to establish the normative values for latencies of Wave I, III, V and interpeak latencies of I-- III, III--V and I--V for younger infants. Methods Click auditory brainstem responses were recorded from infants within 6 months ： 166 infants of 1--months old（269 ears）, 141 2--month old （226 ears）,111 3-- months old（177 ears） ,58 4--months old（96 ears） ,78 5--months old（121 ears） and 45 6--months old（76 ears）. We compared the latencies of wave I, III, V and interpeak latencies of I-- HI, III--V, I--V obtained from infants of differ- ent ages at different stimulus intensities. Results The average threshold of 1 to 6 months infants was 16.18±5.35 dB nHL, the average latency of Wave V was 9.03±0.49 ms. The differences among the thresholds were statistical- ly insignificant（P〈0.05）. Wave I,III and V were noticeable in all ears tested at 80 dB nHL. Wave I disappeared first as the stimulus intensity decreased, and the latencies of Wave I, III and V prolonged; on the contrary,interpeak latencies of I--III, III--V, I--V shortened significantly. At the same stimulus intensity, the lateneies of Wave III, V and the interpeak latencies of I-- llI ,III--V,I--V shortened significantly except for Wave I. When comparing the differences among the testing parameters as a function of each month, we found that there were statistically signifi- cant differences for the latencies of wave III,V and the interpeak latencies of I--III, III--V, I--V before the 4 months old（P〈0.05） ,and there were no significant differences after 4 months old（P〈0.05）. Conclusion It is recommen- ded that 16. 18±5.35 dB nHL be used as the normative references for the evoked threshold of click auditory brain- stem responses for 1-6 month old infants. The development of central nervous system below the inferior calicles is fast before the 4 months old.

关 键 词：婴儿 听性脑干反应 正常参考值 

分 类 号：R764.04[医药卫生—耳鼻咽喉科]