碘131与抗甲状腺药物治疗甲亢疗效对比  

Comparison of Curative Effect of I 131 and Antithyroid Drugs for Hyperthyroidism

作　　者：宋补昌[1] 李晓峰[1] 丰波[1] 

机构地区：[1]山西医科大学第三医院,山西太原030053

出　　处：《中国伤残医学》2013年第11期33-34,共2页Chinese Journal of Trauma and Disability Medicine

摘　　要：目的：探讨碘131和抗甲状腺药物治疗甲状腺功能亢进的疗效。方法：选择2009年5月～2013年5月间于我院就诊的甲状腺功能亢进患者为研究对象，按照治疗方法的不同分为治疗组和对照组，治疗组的患者接受碘131治疗，对照组患者采用抗甲状腺药物治疗。观察治疗1年后2组患者的有效率和复发情况。结果：治疗1年后，治疗组的有效率为92．86％，观察组的有效率为65．85％，差异有统计学意义（P〈0．05）。治疗组的复发率为2．38％，观察组的复发率为19．51％，差异有统计学意义（P〈0．05）。结论：碘131是一种治疗甲状腺功能亢进的安全可靠、疗效明显的方法，可以在临床上推广使用，但其远期疗效仍需进一步的探讨。Objective ：To explore the curative effect of I131 and antithyroid drugs for hyperthyroidism. Methods：The patients of hy- perthyroidism visiting in the endocrinology department of our hospital from May 2009 to May 2012 were taken as the study objects. The patients were grouped into case and control. The case group was treated with I 131, and the control group were treated with antithyroid drugs. The observation indexes were effective rate and recurrence rate of the patients. Results：The effective rate of case group was 92. 86%, the effective rate of control group was 65.85%, the difference was statistically significant（ P 〈 0.05）. The recurrence rate of case group was 2.38%, the recurrence rate of control group was 19.51%, the difference was statistically significant （ P 〈 0.05 ）. Conclusion： I131 was a safe, reliable and effective treatment for hyperthyroidism, can be generalized and used in clinical practice.

关 键 词：碘131 抗甲状腺药物 甲状腺功能亢进 疗效 

分 类 号：R581.1[医药卫生—内分泌]