参芪活血方联合肤康胶囊治疗系统性硬皮病皮肤硬化92例  

On the Treatment of 92 Cases of Systemic Scleroderma with Shenqi Huoxue Formula combined with Fukang Capsule

作　　者：屠文震[1] 陈冬冬[1] 

机构地区：[1]上海市中西医结合医院,上海200082

出　　处：《风湿病与关节炎》2013年第11期9-11,共3页Rheumatism and Arthritis

摘　　要：目的:观察参芪活血方对硬皮病皮肤硬化的治疗作用。方法:将176例系统性硬皮病硬化期患者随机分为治疗组92例和对照组84例,治疗组给予自拟参芪活血方和肤康胶囊口服治疗,对照组给予青霉胺口服治疗。观察治疗前后皮肤硬度积分、关节功能积分的变化,并比较两组疗效。结果:两组患者治疗后皮肤硬化、关节功能积分较治疗前均有明显降低(P<0.01),且治疗组疗效优于对照组(P<0.01)。结论:参芪活血方能有效改善硬皮病患者皮肤硬化及关节功能,副作用小,有较大的临床价值。Objective：To investigate the therapeutic effect of shenqi huoxue formula on systemic scleroderma.Methods：176 patients with systemic scleroderma in sclerotic phase were randomly divided into the therapy group （92 cases） and the control group （84 cases） ,with the former treated with shenqi huoxue formula combined with fukang capsule and the latter with penicillamine orally.Scores of skin sclerosis and joint function were observed before and after treatment, and the therapeutic effects between two groups were compared Results：The scores of skin sclerosis and joint function of the two groups decreased significantly than those before the treatment （P 〈 0.01） ,the therapy group better than the control group （P 〈 0.01） .Conclusion：Shenqi huoxue formula could effectively improve skin sclerosis and joint function of patients with scleroderma,with little side effects and great clinical value

关 键 词：系统性硬皮病 治疗 参芪活血方 肤康胶囊 疗效 

分 类 号：R593.25[医药卫生—内科学]