颈动脉超声对监控精神病患者心血管疾病风险的价值  

The value of carotid artery ultrasound monitoring of psychiatric patients with cardiovascular disease risk

作　　者：李卓丽[1] 谢锐君[1] 刘继元[1] 邓妍[1] 刘榴[1] 余晓仪[1] 

机构地区：[1]广州医科大学附属脑科医院,510370

出　　处：《广州医药》2013年第6期24-26,共3页Guangzhou Medical Journal

基　　金：广州市医药卫生科技项目(20131A011088)

摘　　要：目的探讨颈动脉超声对监控精神病患者心血管疾病风险的价值。方法收集16～50岁重性精神病患者(分裂症、双相障碍、抑郁症)109例作为研究组,91例非精神病患者作为对照组。常规超声测量颈动脉内中膜厚度(IMT)及检测血脂TG、TC。结果研究组与对照组TG之间的差异有统计学意义(P<0.05)。31～40岁男性研究组、女性研究组平均内中膜厚度(IMTmean)、最大内中膜厚度(IMTmax)高于同性别对照组,差异均有统计学意义(P<0.05)。少于30岁的男性研究组IMTmax与男性对照组相比较,差异无统计学意义。41～50岁的男性两组间、女性两组间IMTmeam、IMTmax差异均无统计学意义(P>0.05)。小于30岁女性两组IMTmeam、IMTmax差异无统计学意义(P>0.05)。小于30岁的男性两组间IMTmeam差异无统计学意义(P>0.05)。结论 IMT能评估重性精神病患者早期动脉硬化,颈动脉IMT可以纳入为精神病患者心血管疾病风险的指标。Objective To evaluate the value of carotid artery ultrasound monitoring the cardiovascular disease risk of psychiatric patients. Methods 109 patients with severe mental disease （schizophrenia, bipolar disorder, depression） were included as the study group. A total of 91 volunteers without psychosis were set as the control group. The age ranged from 16 to 50 years. Conventional ultrasound to measure carotid artery intima-media thickness （ IMT）, and total cholesterol （ TC）, triglye- eride （TG） were detected. Results The differences between study group and the control group in TG were statistically signif- icant （ P 〈 0. 05 ）. The mean intima-media thickness （IMTmean） and the max intima-media thickness （IMTmax） in study group （31 -40 years） were significantly higher than the control group. It also had significant differences between male and female （P 〈0.05）. But there were no statistically differences in IMTmean and IMTmax between male and female （41 ~ 50years） （P 〉 0. 05 ）. The difference of female （ 〈 30 years） had no statistical difference between IMTmean, IMTmax （ P 〉 0.05 ）. There were no statistically significant differences in IMTmean of male （ 〈 30 years） either. （ P 〉 0. 05 ）. Conclusion IMT can evaluate the pre-plaque atherosclerosis patients with serious mental illness, carotid IMT can possibly be the indicators of mental disease patients with cardiovascular disease risk.

关 键 词：颈动脉内中膜 精神病 心血管疾病 

分 类 号：R445.1[医药卫生—影像医学与核医学]