潘生丁联合孟鲁司特钠治疗小儿呼吸道合胞病毒感染毛细支气管炎的疗效  

Curative Effect of Montelukast Sodium Combined with Dipyridamole on RSV Bronchiolitis in Children

作　　者：袁高乐[1] 刘赟[1] 

机构地区：[1]南昌大学第一附属医院儿科,南昌330006

出　　处：《实用临床医学（江西）》2013年第8期59-61,共3页Practical Clinical Medicine

摘　　要：目的探讨潘生丁联合白三烯受体拮抗剂孟鲁司特钠治疗呼吸道合胞病毒感染的小儿毛细支气管炎的临床疗效。方法将50例呼吸道合胞病毒感染的毛细支气管炎患儿随机分为2组:对照组25例采用一般常规综合治疗,治疗组25例在常规综合治疗基础上加用潘生丁与孟鲁司特钠治疗。观察2组患儿呼吸困难、哮鸣音、啰音、咳嗽等临床症状消失时间,比较2组住院时间及临床疗效。结果治疗组临床症状消失时间与住院时间较对照组均明显缩短(P<0.05或P<0.01)。治疗组显效率、总有效率均显著高于对照组(76%比40%,P<0.01;92%比68%,P<0.05)。结论对呼吸道合胞病毒感染的小儿毛细支气管炎,在常规综合治疗基础上采用潘生丁联合孟鲁司特钠治疗,疗效确切。Objective To investigate the clinical effect of montelukast combined with leukotriene receptor antagonist dipyridamole on respiratory syncytial virus （RSV） bronchiolitis in children. Methods Fifty children with RSV bronchiolitis were randomly given routine treatment （control group, n=25） or in combination with montelukast and dipyridamole （treatment group, n=25）. Disappearance time of clinical symptoms （dyspnea, wheeze, rales, Cough, etc.）, hospital stay and clinical efficacy were compared between the two groups. Results Compared ith control group, disappearance time of clinical symptoms and length of hospital stay obviously decreased in treatment group （P〈0.05 or P〈0.01）. In addition, both significant efficiency and total efficiency in treatment group were obviously higher than those in control group （76% and 92% vs 40% and 68%, respectively; P〈0.05）. Conclusion The combined treatment with montelukast and dipvridamole is effective for RSV bronchinliri~

关 键 词：潘生丁 孟鲁司特钠 呼吸道合胞病毒 毛细支气管炎 小儿 

分 类 号：R725.6[医药卫生—儿科]