阿苯达唑片的质量评价及临床应用  

Clinical application and evaluation of albendazole tablets.

作　　者：马好斌[1] 

机构地区：[1]焦作煤业(集团)有限责任公司中央医院,河南焦作454000

出　　处：《河南中医》2013年第B10期56-56,共1页Henan Traditional Chinese Medicine

摘　　要：目的：就阿笨迭唑片的质量评价及临床应用进行探讨。方法：对本单位及市售的3个厂家的产品进行了质量比较。结果：三个厂家阿笨达唑片的溶出度均符合《中华人民共和国药典））（2005年版）规定的45min〉65．00％的规定，其中最高的为A厂：69．48％，最低的为C厂：65．79％。经统计学处理，三者与药典规定的标准65．00％比较，差异均无显著性意义（P〉0．05）。三个厂家阿苯迭唑片的含量测定结果：A厂为98．76％，B厂为93．12％，C厂为97．83％。三者均符合药典规定：含量为标示量的90。0～110．0％。结论：阿苯达唑是我国卫生部和世界卫生组织所主要推荐的驱虫药，具有方便、安全、高效、广谱等多种特性，属于典型的苯骈咪唑类药物。阿苯迭唑对于蛲虫、钩虫、蛔虫等为代表的多种蠕虫感染有良好疗效。Objective： To evaluate the clinical application and quality evaluation of albendazole tablets. Methods： 3 of the unit and the commercially avail- able products are quality comparison. Results： three manufacturers of albendazole tablets solubility are in line with the ＂Pharmacopoeia of the people＇s Repub- lic of China＂ （2005 Edition） provisions of 45min〉65.0%, the highest for the A factory： 69.48%, the lowest for the C factory.. 65 . 79~. After statistics processing, compared with the Pharmacopoeia standards stipulated in three of 65 . 0%, have no significant difference （P〉0.05）. Three manufacturers of al bendazole in albendazole tablets were： A factory for 98. 76%,B factory for 93.12%, C factory for 97.83%. Three are in line with the Pharmacopoeia： con- tent is marked in the amount of 90.0-110. 0%. Conclusion.. Anthelmintic albendazole is China＇s Ministry of health and who are recommended, with conven- ient, safe, efficient, broad--spectrum and other characteristics, which belongs to the typical benzimidazole drugs. Albendazole for hookworm, Ascaris, En- terobius vermicularis and other worms as the representative of the infection has a good curative effect.

关 键 词：阿苯达唑片 质量评价 临床应用 

分 类 号：R453[医药卫生—治疗学]