孕前肥胖与妊娠期糖尿病关系的研究  

Study on the relationship between pre-pregnancy obesity and gestational diabetes mellitus.

作　　者：毛淑芳[1] 王建华[2] 狄荣军 金晓娥 

机构地区：[1]承德医学院预防医学教研室,067000 [2]天津医科大学流行病学教研室,300070 [3]承德市妇幼保健院,067000 [4]承德市双桥区计划生育技术服务站,067000

出　　处：《中国实用妇科与产科杂志》2000年第11期661-662,共2页Chinese Journal of Practical Gynecology and Obstetrics

基　　金：国家自然科学基金!资助项目 (项目号 39970 6 6 1)

摘　　要：目的　探讨孕前肥胖与妊娠期糖尿病 (GDM )之间的关系。方法　采用队列研究对 6 14例孕妇进行调查 ,于孕 2 4～ 2 8周对其进行GDM筛检。结果　孕前体质指数 (BMI)≥ 2 5kg/m2 的人群GDM发病率高于BMI<2 5kg/m2 的人群 ,随孕前腰围增大 ,GDM发病率逐渐升高。非条件Logistic回归分析表明 ,孕前BMI、孕前腰围是GDM重要的有统计学意义的危险因素。结论　孕前肥胖是GDM独立的危险因素 ,控制孕前肥胖是预防GDM发生的重要措施。Objective To investigate the relationship between pre-pregnancy obesity and gestational diabetes mellitus(GDM).Methods A cohort study was performed in 614 pregnant women.They were screened for GDM at 24 to 28 weeks of pregnancy.Results The incidence of GDM raised significantly in the women with pre-pregnanct BMI≥25kg/m 2 than those with BMI<25kg/m 2.The thicker the waist circumference,the higher the incidence.Non-conditional logistic regression analysis revealed that pre-pregnanct BMI and waist circumference were significantly related to GDM.Conclusion Pre-pregnancy obesity is risk factor to GDM.Prevention of pre-pregnancy obesity might have some preventive impact on the incidence of GDM.

关 键 词：糖尿病 孕前肥胖 妊娠合并症 相互关系 

分 类 号：R714.256[医药卫生—妇产科学] R587.202[医药卫生—临床医学]