Cube FLAIR序列在颅脑疾病中的应用研究  

Application study of Cube FLAIR sequence in craniocerebral diseases

作　　者：张顺[1] 张水震 覃媛媛[1] 汤翔宇[1] 朱文珍[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院放射科,武汉430030

出　　处：《放射学实践》2013年第11期1123-1127,共5页Radiologic Practice

基　　金：国家自然科学基金(81171308);国家"十二五"科技支撑计划项目(2011BAI08B10)

摘　　要：目的:探讨Cube FLAIR序列在颅脑疾病中的应用。方法:本研究纳入40例研究对象,其中健康志愿者30例,颅脑疾病患者10例,包括颅内出血4例,颅神经病变2例,颅内结核3例,室间孔区占位1例。30例志愿者在1.5T磁共振扫描仪上完成T2FLAIR序列(1.5TFLAIR),并同时在3.0T上完成T2FALIR序列(3TFLAIR)及Cube FLAIR序列扫描;10例颅脑疾病患者在3.0T上完成T2FALIR序列及Cube FLAIR序列扫描。Cube FALIR序列扫描完后行多平面重组及常规横轴面重组,并与常规T2FLAIR序列(1.5TFLAIR、3TFLAIR)进行对比。结果:颅内脑池、脑沟在3.0T场强下较1.5T场强更容易出现高信号脑脊液流动伪影,差异有统计学意义(χ2=23.227,P<0.05)。4例颅内出血患者Cube FLAIR序列较T2FLAIR序列更清晰的显示了其出血部位及出血量。Cube FLAIR序列直观显示了视神经炎患者肿胀、增粗的视神经以及三叉神经痛患者γ刀治疗后局部的胶质增生改变。Cube FLAIR序列增强后清晰的显示了颅内结核患者结核灶的分布、脑膜的播散,且较常规增强扫描显示的病灶更多、范围更广。结论:Cube FLAIR序列在颅脑疾病诊断中有重要的应用价值,可作为常规序列应用于中枢神经系统疾病的临床诊断。Objective：To explore the value of Cube FLAIR sequence in craniocerebral diseases. Methods：Forty sub-jects （30 volunteers and 10 patients） were included in this study. The patients were composed of 4 cases of intracranial hem-orrhage,2 cases of cranial neuropatby, 3 cases of intracranial tuberculosis, and 1 case of mass in the interventricular fora-men. Thirty volunteers underwent 1.5T FLAIR scan by using 1.5T MR scanner and 3T FLAIR as well as sagittal Cube FLAIR sequence scan by using 3T MR scanner consecutively as one examination. Ten patients underwent 3T FLAIR and sagittal Cube FLAIR imaging with the 3T MR scanner. Multi-planar reconstruction and axial reconstruction were completed after Cube FLAIR scan in order to compare with conventional T2 FLAIR sequence. Results： High signal CSF flow artifacts were more obvious in the cerebral cisterns and sulci in 3.0Tesla than those in 1.5Tesla （X^2 = 23. 227,P〈0.05）. Compared with T2 FLAIR,Cube FLAIR not only clearly demonstrated the bleeding site and amount in the intracranial hemorrhage but also easily displayed the swelling and thickening of optic nerve in optic neuritis patients and local gliosis changes in the tri- geminal nerve after gamma-knife treatment. The enhanced Cube FLAIR sequence clearly depicted the distribution of tuber-culous lesions and the meningeal spread in the intracranial tuberculosis patients as well as a much wider range compared with conventional enhanced T1 WI. Conclusion：Cube FLAIR sequence can be used as a conventional sequence in the diagnosis of central nervous diseases.

关 键 词：磁共振成像 颅脑疾病 蛛网膜下腔出血 诊断 

分 类 号：R445.2[医药卫生—影像医学与核医学] R742[医药卫生—诊断学]