用光镊研究稳恒磁场对血红细胞的活性影响  

Research of activity decay of red blood cells in static magnetic field with optical tweezers

作　　者：李雷[1] 

机构地区：[1]南京理工大学紫金学院,南京210046

出　　处：《激光技术》2013年第6期799-802,共4页Laser Technology

摘　　要：为了研究稳恒磁场对离体血红细胞的活性衰变产生的影响,采用非接触、无损伤的光镊技术进行了实验与分析。光镊中的高斯激光光束作用使红细胞发生形变,待细胞稳定后切断光路,得到形变血红细胞的相对形变量值,该量值大小与红细胞活性相关;对比了正常离体血液与静置于稳恒磁场中的红细胞活性衰变规律。结果表明,0.20T稳恒磁场可以提高红细胞的变形能力,增强红细胞的活性;同时加速了细胞体内能量的消耗,因离体环境没有能量的补充,能量的消耗加速了红细胞的衰老。这一结果为磁场对细胞的活性影响和动力学分析提供了一些参考。Optical tweezers was used to study the changing rule of the activity of the red blood cells in static magnetic field. Red blood cells irradiated by Gaussian laser beam were deformed. When the laser was cut off, the relative deformation value of blood cells was obtained, which was associated with the cells＇ activity. After comparing the decay process of cells activity between static red blood cells and red blood cells in magnetic field, the results showed the activity of the red blood cells increased by 0.20T magnetic field, meanwhile the cells＇ energy consumption increased. The death of cells has accelerated because of energy consumption. The research can provide valuable reference for the study of cells viability and dynamic analysis.

关 键 词：生物光学 光镊 红细胞 磁场 活性衰变 

分 类 号：Q631[生物学—生物物理学]