中医药促进神经干细胞增殖与分化用于抗脑缺血损伤的研究进展  

Research Progress in Improving Proliferation and Differentiation of Neural Stem Cells by Traditional Chinese Medicine on Cerebral Ischemia Injury

作　　者：雷丽萍[1,2] 刘旺华[1,2] 周鸿图[3] 周小青[1,2] 

机构地区：[1]湖南中医药大学第一临床医学院,长沙410007 [2]湖南中医药大学中医诊断学教研室,长沙410007 [3]湖南中医药大学第一附属医院干部保健内科,长沙410007

出　　处：《医学综述》2013年第19期3466-3469,共4页Medical Recapitulate

基　　金：湖南省教育厅科研基金(12B097);湖南省科技厅重点项目(2011FJ2013);中医诊断学重点学科资助项目(13ZD05);中医诊断学实验室资助项目(12SY03)

摘　　要：长期以来,运用传统中医药方法治疗脑缺血及其后遗症有着独特优势,在临床也取得了较好疗效,但具体作用机制和作用靶点还需进一步研究证明。神经干细胞可永久自我更新,具有多向分化潜能。中医药可通过多种途径促进神经干细胞的增殖与分化,从而有效治疗神经组织的缺血性损伤,为神经再生的治疗开辟了新方向,已成为抗脑缺血损伤研究的焦点。For a long time, it is clinically effective for the unique advantages of traditional Chinese medi- cine in the treatment of cerebral isehemia and sequelae. But the specific mechanism and target of action still need further evidence to prove. Neural stem cells（NSCs） have developed a new research field for the strate- gies of nerve regeneration treatment because of the biological characteristics of self-renewal and the multiple differentiation potential. Traditional Chinese medicine can promote NSCs proliferation and differentiation thruugh various approaches, and treat ischemic injury of nerve tissue, which has opened a new direction ot＇ nerve regeneration and become a focus of anti-cerebral ischemia injury in neuroscience.

关 键 词：中医药 脑缺血 神经干细胞 增殖 分化 

分 类 号：R285.5[医药卫生—中药学]