哺乳动物冬眠的研究进展  

Progress in study of mammalian hibernation

作　　者：杨明[1] 彭霞[2] 宋士一[1] 

机构地区：[1]沈阳师范大学化学与生命科学学院,沈阳110034 [2]沈阳师范大学实验教学中心,沈阳110034

出　　处：《沈阳师范大学学报（自然科学版）》2013年第4期433-441,共9页Journal of Shenyang Normal University:Natural Science Edition

基　　金：国家自然科学基金资助项目(31170380);沈阳师范大学实验教学中心主任基金资助项目(sy201003)

摘　　要：哺乳动物具有较高的代谢率、发达的神经体液调节系统,所以能够维持高而恒定的体温。但有些哺乳动物在寒冷和食物资源短缺的冬季或其他不良环境条件下,能自发降低代谢率和体温,进入冬眠状态。综述了国内外哺乳动物冬眠的研究历史和现状,并从冬眠物种的系统学分布、冬眠的原因及其进化和适应意义入手,概括论述了哺乳动物冬眠的代谢抑制及其能量收益、冬眠代谢抑制的生化及分子生物学机制等方面的研究进展,并概括介绍哺乳动物冬眠对医学和人类健康的启示。Mammals can maintain a higher and constant body temperature because of their higher metabolic rate and developed neurohumoral regulation system. But some mammals in cold and food shortages winter time or other adverse environmental conditions can spontaneously reduce their metabolic rate and body temperature, entering a state of hibernation. In this paper, we review the study history and current status of mammalian hibernation, the systimatic distribution of hibernating species, the evolutionary and adaptive significance of mammals hibernation, the progress metabolic inhibition and energy saving of mammalian hibernation, the biochemical and molecular mechanism of metabolism inhibition of mammals hibernation, and summarized the enlightenment of mammals hibernation on human health and medicine.

关 键 词：冬眠 哺乳动物 代谢 能量 分子机制 

分 类 号：Q958.1[生物学—动物学]