碘对甲状腺结节性疾病影响的相关性研究  

Correlative studies of iodine on thyroid nodular diseases

作　　者：陶霖玉[1] 李杏[1] 黄娟[1] 谢佩霞[1] 高旭红[1] 齐柯[1] 

机构地区：[1]广东医学院附属南山医院甲乳外科,广东深圳518052

出　　处：《中国现代医学杂志》2013年第27期82-85,共4页China Journal of Modern Medicine

基　　金：深圳市南山区科技局2010年科研项目(No:2010035)

摘　　要：目的探讨碘对甲状腺结节性疾病的影响。方法采用"尿碘定量检测法"对患有甲状腺结节(术前组)、已行甲状腺手术(已手术组)和正常人群(正常对照组)的尿碘水平进行检测。结果三组尿碘水平构成比不同(P<0.001);疾病组尿碘中位数为碘过量(323.05μg/L),已手术组尿碘中位数为碘充足(177.11μg/L),正常对照组尿碘中位数为碘超足量为(261.84μg/L),疾病组尿碘中位数与已手术组尿碘中位数及正常对照组尿碘中位数比较差异均有显著性(P<0.05);已手术组尿碘中位数与正常对照组尿碘中位数比较无显著性差异(P>0.05)。结论甲状腺结节性疾病患者碘过量,既往患甲状腺结节性疾病已行手术切除的患者碘充足,正常人群碘超足量;甲状腺结节性疾病的发病可能与碘摄入过量有关;甲状腺结节性疾病患者行手术治疗可能可以使体内碘水平下降。[Objective] To explore the impact of iodine on thyroid nodular disease. [Methods] The value of urine iodine was measured in thyroid nodular diseases patients （disease group）, nodular thyroid postoperative patients （postoperative group） and normal people （control group） by the urine iodine quantitative detection method. [ Results ] Comparing the constituent ratio of urine iodine levels, three groups have different constituent ratio of urine iodine levels （P 〈0.001）. The median of urine iodine （MUI） in disease group was excessive iodine （323.05 μg/L）, the postoperative group was adequate iodine （177.111xg/L）, the control group was more than adequate iodine（261.84 μg/L）. The median of urine iodine in disease group was higher than the control group and postoperative group, the difference had statistical significance. [ Conclusions] The patients with thyroid nodular diseases suffer excessive iodine, the patients with nodular thyroid postoperative suffer adequate iodine, health People suffer more than adequate iodine. The incidence of thyroid nodular disease may be related to excessive iodine intake. The patients with thyroid nodular disease underwent surgical treatment may be able to make the iodine levels down.

关 键 词：碘 尿碘 甲状腺结节性疾病 碘摄入量 

分 类 号：R581[医药卫生—内分泌]