PCT与血培养联合检测新生儿败血症的诊断价值  

Diagnosis value of PCT combined with blood culture for neonatal sepsis

作　　者：周卫萍[1] 刘莺[1] 唐萍[1] 李菲[1] 顾宝珠[1] 冯欢欢[1] 刘征 

机构地区：[1]西安高新医院新生儿科,陕西西安710075 [2]长安医院,陕西西安710016

出　　处：《中国妇幼健康研究》2013年第5期766-767,共2页Chinese Journal of Woman and Child Health Research

摘　　要：目的探讨降钙素原(PCT)对新生儿败血症早期诊断的价值。方法对2010年1月至2011年12月西安高新医院新生儿重症监护室收治的125例临床诊断为新生儿感染的患儿用免疫色谱法进行降钙素原检测,比较血培养结果与降钙素原的关系。结果败血症患儿降钙素原阳性率占97.1%,局部感染组阳性率占9.7%,非感染阳性率占5.6%。降钙素原数值在败血症患儿早期明显增高,败血症患儿与局部感染及非感染患儿之间降钙素原数值有显著性差异(x^2值分别为16.074、3.953、4.970、5.050,均P<0.05)。新生儿败血症降钙素原阳性率为97.1%,明显高于血培养的17.1%(x^2=80.923,P<0.05)。结论降钙素原对新生儿败血症的诊断敏感度高,特异性强,对新生儿败血症早期诊断有很好的应用价值。Objective To explore the value of procalcitonin （ PCT） for early diagnosis of neonatal sepsis .Methods From January 2010 to December 2011, 125 neonates were diagnosed with neonatal infection in clinics and treated in NICU in Xi ＇ an Gaoxin Hospital.Immune chromatography was used for PCT testing , and the relationship between calcitonin and blood culture results was explored .Results The positive rate of PCT in neonates with sepsis was 97.1%, that was 9.7%in local infection group and 5.6%in non-infectious group .PCT value increased significantly in early sepsis of neonates , and it was significantly different from that of neonates with local infection and non -infected neonates（χ^2 value was 16.074, 3.953, 4.970 and 5.050, respectively, all P〈0.05）.The positive rate of PCT in neonatal sepsis was 97.1%, which was obviously higher than that of blood culture （17.1%） （χ^2 =80.923, P 〈0.05）.Conclusion PCT is sensitive for diagnosis of neonatal sepsis , and it has high specificity for early diagnosis of neonatal sepsis .

关 键 词：降钙素原 败血症 新生儿 感染 

分 类 号：R722[医药卫生—儿科]