1550nm铒玻璃点阵激光与Nd:YAG长脉宽1064nm激光治疗痤疮凹陷性瘢痕的疗效与安全性比较  

Comparative Study on the Efficacy of Fractional Erbium Glass Laser Therapy and Nd: YAG Laser Long-pulse 1064nm Therapy on Atrophic Acne Scars

作　　者：王琼玉[1] 李蕊联[1] 马云云[1] 邹兴伟[1] 王琼[1] 应朝霞[1] 王永贤[1] 

机构地区：[1]西安交通大学医学院第二附属医院皮肤科,陕西西安710004

出　　处：《中国皮肤性病学杂志》2013年第11期1117-1119,共3页The Chinese Journal of Dermatovenereology

基　　金：西安市科技计划项目(SF08005-2)

摘　　要：目的在不使用药物的情况下比较1 550nm铒玻璃点阵激光与Nd:YAG长脉宽1 064nm激光治疗痤疮凹陷性瘢痕的疗效和安全性。方法 40例面部痤疮凹陷性瘢痕患者不使用任何药物,随机分为1 550nm铒玻璃点阵激光治疗组和Nd:YAG长脉宽1 064nm激光治疗组,每组20例,间隔3周治疗1次,共3次。治疗前后均以ECCA权重评分表对痤疮凹陷性瘢痕部位进行评分统计。结果所有患者痤疮凹陷性瘢痕均有不同程度改善,均未出现严重不良反应,两组治疗前后ECCA权重评分均明显下降,经方差分析检验,差异有统计学意义(P<0.05);铒玻璃点阵激光治疗组治愈率61.54%,Nd:YAG长脉宽1 064nm激光治疗组治愈率26.42%,两组疗效比较差异有统计学意义(P<0.05)。结论 1550nm铒玻璃点阵激光治疗痤疮凹陷性瘢痕疗效优于Nd:YAG长脉宽1 064nm激光,安全性高,疗效确切,为痤疮凹陷性瘢痕的治疗提供了一种有效的选择。Objective To compare the efficacy of fractional Erbium glass laser （ 1 55Ohm） and Nd ： YAG long-pulse I 064nm laser therapy for facial atrophic Acne scars. Methods Forty patients with facial atrophic acne scars were randomly divided into fractional Erbium glass laser（ 1 550nm） therapy group and Nd：YAG long- pulse 1 064nm laser therapy group. All cases was given a total of three sessions laser treatment at 3-week in- tervals. Comparative photographs were taken using ECCA grading scale to identify and quantify facial atroph- ic scars. The clinical efficacy were observed. Results All of the cases obtained different degree of improve- ment after 3 times treatment. The cure rate in fractional Erbium glass laser （ 1 550nm） therapy group was 61.54% ; The cure rate in Nd：YAG long-pulse l 064nm laser therapy group was 26.42%. No severe side effect was observed. There were significance between two groups （ P 〈 0.05 ）. Conclusion Fractional Erbi- um glass laser（ 1 550nm） is effective and safe in the treatment of facial atrophic acne scars. It is better than Nd：YAG long-pulse 1 064nm laser therapy. It provides a new therapeutic option for atrophic acne scars.

关 键 词：凹陷性痤疮瘢痕 1 550nm铒玻璃点阵激光 ND YAG长脉宽1 064nm激光 

分 类 号：R758.733[医药卫生—皮肤病学与性病学]