云南某地区新型毒品使用人群HIV-1感染率及其影响因素分析  

Study on Prevalence and Influencing Factors of Human Immunodeficiency Virus Infections among the New Type Narcotics Users in a Region of Yunnan Province

作　　者：高良敏[1] 赵金仙[1] 杨江华[2] 鲁建波[1] 凌剑波[2] 陈黎跃[1] 段洪华[2] 陈良[1] 

机构地区：[1]玉溪市疾病预防控制中心,云南玉溪653100 [2]江川县疾病预防控制中心,云南江川652600

出　　处：《中国皮肤性病学杂志》2013年第11期1130-1133,共4页The Chinese Journal of Dermatovenereology

基　　金：2011年云南省防治艾滋病创新项目(2011009)

摘　　要：目的了解新型毒品使用人群艾滋病病毒感染率及其影响因素，为探索有效的新型毒品使用人群艾滋病防治措施提供科学参考。方法采用滚雪球抽样、整群抽样、偶遇抽样分别调查来自社区、拘留所、VCT门诊求询的新型毒品使用者，并进行血清学HIV-1检测及Logistics影响因素分析。结果在454例新型毒品使用者中，HIV-1感染率为6．17％（95％CI：3．95—8．38），感染率在不同“年龄”、“通常情况下，使用一次的消费”、“最近一次使用新型毒品后与发生性行为”、“最近三个月，使用新型毒品后与发生过性行为”间的比较，差异均有统计学意义（P均〈0．05）。Logistics回归分析结果：年龄、文化程度均与HIV感染率为负相关，OR分别为0．016和0．033；使用新型毒品的时间与感染率呈正相关，OR为6．807；经常在家里、朋友家里、小旅馆使用、“最近三个月，使用后与多人发生过性行为”为感染HIV的危险因素，OR分别为27．058，9．689，89．747和68．993；“最近半年，经常在小旅馆使用”、“最近三个月，使用后与多人发生过性行为”为感染HIV最主要因素，标准化偏回归系数分别为1．567和1．015。结论HIV-1感染在新型毒品使用人群中不容忽视，而且存在多种危险因素。Objective To understand the prevalence and influencing factors of HIV-1 infections among the new type narcotics users in a region of Yunnan Province, and to provide some scientific reference for exploring the ef- fective prevention and treatment measures against AIDS of those new type narcotics users. Methods Snow- ball sampling, cluster sampling and accidental sampling were adopted to survey the new type narcotics users in the community, detention center, and inquirers seeking consultation at the voluntary counseling and tes- ting（VCT） Clinic. All volunteers were tested for HIV infection. Logistics regression analysis was conducted to elucidate risk factors of HIV infections. Results Among 454 new type narcotics users, the HIV-1 infection rate was 6.17% （95% CI：3.95 -8.38）. The HIV-1 infection rates were of statistical significance by compa- ring different variables in ＂age＂, ＂using drug once under normal circumstances＂, ＂most recent sexual act after having had used new type of narcotics＂, ＂had sexual act in the past three months after having had used new type of narcotics＂. All P 〈 0.05. The results of Logistics regression analysis：age and education level were associated with HIV infection rate was negatively correlated. The OR were 0. 016 and 0. 033 respective- ly. The length of time using the new type narcotics was positively correlated with infection, OR was 6. 807. Often using new type drugs at home, at a friend＇s house or a small inn, or ＂had sexual act with multiple peo- ple after having used drugs in the past three months＂ were the risk factors for HIV infection, The OR were 27. 058, 9.689, 89.747 and 68. 993 respectively; ＂Used drug in a small hotel in the past six months＂ and ＂had sexual act with multiple people after having used drug in the past three months＂ were the main factors in the HIV infection, and the standardized partial regression coefficients were 1. 567 and 1. 013 respectively. Conclusion The HIV-1 infection rate was affected by many risk factor

关 键 词：艾滋病 新型毒品 流行病学研究 

分 类 号：R512.91[医药卫生—内科学] D669.8[医药卫生—临床医学]