金坛市1458例已婚妇女3年宫颈癌筛查情况分析  

Analysis of the results of 1458married women received three-year cervical cancer screening in Jintan area

作　　者：薛芸[1] 洪颖[1] 贺俊霞[2] 李倩[3] 赵方辉[4] 彭琦[2] 金凤[2] 徐爱玲 

机构地区：[1]南京大学医学院附属鼓楼医院妇产科,江苏省210008 [2]南京中医药大学中西医结合鼓楼临床医学院 [3]南京医科大学鼓楼临床医学院 [4]中国医学科学院肿瘤所 [5]金坛市疾控中心

出　　处：《江苏医药》2013年第22期2677-2679,共3页Jiangsu Medical Journal

基　　金：江苏省卫生厅课题(H200803);江苏省科技厅科技支撑计划社会发展课题(BE2012606);中国癌症基金会课题"GSK宫颈癌预防性疫苗临床研究"

摘　　要：目的分析金坛市随访人群连续3年宫颈上皮内瘤变(CIN)发病率的变化趋势。方法选择金坛地区自愿接受筛查的18-25岁已婚妇女1458例,采用宫颈液基细胞学检查(TCT)。其结果为不能明确临床意义(ASCUS)者并行高危型HPV-HC2检测,结果阳性者及低度上皮内瘤变(LSIL)以上者均结合阴道镜检查和活检病理诊断。结果 2009年、2010年和2011年宫颈高危病变(HSIL)发病率分别为2.19%、1.60%和0.24%,CIN发病率依次为3.36%、1.89%和0.79%。结论通过每年对高危人群进行宫颈癌及癌前病变的筛查,金坛地区CIN新增发病率有逐年降低趋势。筛查是预防和控制宫颈癌的主要手段。Objective To analyze the incidence rate variation of cervical intraepithelial neoplasia （CIN） during the years of 2009 to 2011 in Jintan area. Methods Cervical liquid-based cytology（TCT） examination was performed in 1458 married women aged from 18 to 25 years old living in Jintan district. The wemen with atypical squamous cells of undetermined significanc （ASCUS） reported by TCT screening were given HPV-DNA tests, of whom the patients with positive AS（US and lower grade squamous intraepithelial lesions（LSIL） received colposcopy and cervical biopsy. Results The incidence rates of high-risk cervical disease（HSIL） in the year 2009,2010 and 2011 were 2.19%, 1.60% and 0. 24~, respectively. The total incidence rates of CIN were 3.36 %, 1.89 % and 0. 79%, respectively,in the three years. Conclusion By cervical cancer screening, the morbidity of CIN has a tendency in the year 2009,2010 and 2011, indicating that screening is an effective method to prevent and control cervical cancer.

关 键 词：宫颈液基细胞学检查 宫颈癌 宫颈上皮内瘤变 

分 类 号：R711[医药卫生—妇产科学]