超声瞬时波强度与心导管评价左心室收缩功能的相关性研究  

Correlation between Ultrasound Wave Intensity and Cardiac Catheterization in Evaluating Left Ventricular Systolic Function

作　　者：张辉[1] 郑荣琴[1] 钱孝贤[2] 郝宝顺[2] 张成喜[2] 

机构地区：[1]广州市中山大学附属第三医院超声科,中山大学超声与介入治疗研究所,广州市510630 [2]广州市中山大学附属第三医院心内科

出　　处：《中国超声医学杂志》2013年第11期1028-1031,共4页Chinese Journal of Ultrasound in Medicine

基　　金：广东省科技计划项目基金资助(No.2011B061300005)

摘　　要：目的了解颈动脉超声瞬时波强度(WI)与心导管检查,评价兔左心室收缩功能变化中的相关性。方法选择雄性健康新西兰大白兔80只,静脉注射阿霉素后连续观察16周。每周末进行颈动脉WI、心导管检查及心肌细胞凋亡测定。结果颈动脉WI_1与心导管+dp/dt_(max)呈正相关(r=0.94,P<0.01);与心肌细胞AI呈负相关(r=-0.69,P<0.01)。而EF与心导管+dp/dt_(max)呈中度正相关(r=0.53,P<0.05);与心肌细胞AI的相关性无统计学意义(P>0.05)。结论颈动脉超声WI与心导管左心收缩功能参数相关性较高,能较好地反映左心收缩功能的改变。Objective To explore the correlation between ultrasound carotid artery wave intensity（WI） and cardi- ac catheterization in evaluating left ventrieular systolic function of rabbits. Methods Eighty male healthy New Zealand rabbits were chosen. Adriamycin was injected for 8 weeks, then stopped and observed for anther 8 weeks. Every weekend WI examination, eehocardiography, cardiac catheterization and pathology were performed. Results Wit is positive correlated with q- dp/dtm,x （r~ 0.94, P~ 0.01）, and the AI is negative correlated with Wit （ r = -- 0.69, P 0.01）. EF is positive correlated with q-dp/dtm^x （r= O. 53, P^O. 05）, but the AI is not correlated with EF （P^O. 05 ）. Conclusions Carotid artery ultrasound WI examination is highly positive correlated with cardiac catheterization and could reflect the changes of left ventricular systolic function.

关 键 词：超声 心导管 颈动脉 瞬时波强度 阿霉素 

分 类 号：R540.45[医药卫生—心血管疾病]