结核分枝杆菌几种临床检测方法的比较  

Several Detections of Mycobacterium tuberculosis

作　　者：王玲玲[1] 李辉[2] 谢风[1] 

机构地区：[1]吉林大学中日联谊医院检验科,吉林长春130033 [2]吉林省人民医院

出　　处：《中国实验诊断学》2013年第11期1992-1995,共4页Chinese Journal of Laboratory Diagnosis

摘　　要：目的对TB-Ab、结核PCR、QFT和T-SPOT.TB几种临床检测结核分枝杆菌的常见方法进行比较分析,探讨四种方法对于检测结核病的临床诊断价值。方法对212例结核确诊患者和144例非结核者分别进行TB-Ab、结核PCR、QFT和T-SPOT.TB检测。结果四种方法的敏感度依次为67.9%、73.6%、75.4%和86.8%,特异度分别为72.2%、83.3%、91.7%和88.9%。结论结核感染T细胞免疫斑点试验(T-SPOT.TB)对于结核病的检测具有较高的特异度和灵敏度,可为临床结核病的诊断提供及时有效的依据。Objective To compare and evaluate the clinical significance of the four tests in tuberculosis detection. Methods There are 212 patients of diagnosed TB and 144 patients of non-tuberculosis. They were performed by TB Ab,TB-PCR,QFT and T-SPOT. TB,respectively. Results The sensitivity of TB-Ab,TB-PCR,QFT and T-SPOT. TB tests detecting for diagnosis of TB was 67.9% ,73.6% ,75.4% and 86.8%. The specificity of these tests was 72.2%, 83.3 %, 91.7 % and 88.9%. Conclusion TB-infected T cells spot test is a high sensitive and specific test to diagnose tuberculosis. Therefore,it can provide timely and effective results for the clinical diagnosis of tuberculosis.

关 键 词：结核病 TB-AB 结核PCR QFT T—SPOT TB 

分 类 号：R52[医药卫生—内科学]