CT引导下经皮放射性^(125)I粒子植入治疗恶性肿瘤的临床研究  

CT-guided permanent Iodine-125 seed implantation for the treatment of malignant tumors

作　　者：周定中[1] 曹苏娟[2] 李庆[1] 龙文兴[1] 李艳峰[1] 

机构地区：[1]湘南学院附属医院放射科 [2]湘南学院附属医院肿瘤科,湖南郴州423000

出　　处：《湘南学院学报（医学版）》2013年第3期21-23,共3页Journal of Xiangnan University（Medical Sciences）

基　　金：湖南省教育厅科研项目(12C0891);湖南省卫生厅科研基金(B2012-075);郴州市2011年科技局资助项目

摘　　要：目的探讨CT引导下经皮放射性^(125)I粒子植入治疗恶性肿瘤的临床应用价值。方法回顾性分析35例CT引导下经皮放射性^(125)I粒子植入治疗恶性肿瘤的临床资料。结果 25患者顺利完成手术,无严重并发症,随访2~6月,完全缓解6例(17.14%),部分缓解24例(68.58%),病变稳定2例(5.71%),进展3例(8.57%),未出现放射相关副作用。结论 CT引导下经皮放射性^(125)I粒子植入治疗恶性肿瘤具有创伤少、并发症少、疗效肯定、安全等优点。Objective To observe the application value of CT- guided permanent Iodine- 125 seed implanta- tion for the treatment of malignant tumors. Methods Clinical materials of 35 patients with malignant tumors under- went CT- guided permanent Iodine - 125 seed implantation. Results All patients completed the procedure successfully with no serious complication occurrence. Clinical effects were evaluated after 2 to 6 months later. Among the 35 cases, 17.14 % （6/35） had complete recovered, 68.58 % （ 24/35 ） partial recovered, 5.71% （ 2/35 ） kept stable and 8.57 % （3/35） had progressive, and all were free from radioactive side effects. Conslusion CT - guided permanent Iodine- 125 seed implantation for the treatment of malignant tumors is a minimally invasive, safe, ef- fective and few complications.

关 键 词：^125I粒子 组织间植入 体层摄影术 X线计算机 

分 类 号：R814.42[医药卫生—影像医学与核医学]