鸡传染性喉气管炎病毒DNA疫苗免疫效果观察  

Immune Effect of DNA Vaccine Encoding gB、gC and gD of Avian Infectious Laryngotracheitis Virus

作　　者：孟松树[1] 张绍杰[1] 童光志[1] 

机构地区：[1]中国农业科学院哈尔滨兽医研究所兽医生物技术国家重点实验室,哈尔滨150001

出　　处：《中国预防兽医学报》2000年第3期179-181,共3页Chinese Journal of Preventive Veterinary Medicine

摘　　要：将分别构建的含有鸡传染性喉气管炎病毒王岗株gB、gC和gD基因的重组真核表达质粒及空载体质粒分组肌肉注射雏鸡 ,攻毒后观察免疫保护效果。结果表明 ,重组质粒诱导了免疫应答 ,免疫保护率为 79% 。Chickens were immunized by intramuscular injection of eukaryotic expresstion recombinant plasmids containing gB、gC and gD genes of Infectious Laryngotracheitis Virus WangGang strain.The specific antibody was detected after immunization.Immune effects showed that the immune protection rate of recombinant plasmids reached 79%.This result proved that the DNA vaccine could be used as a addition to prevent ILTV infection.

关 键 词：鸡 传染性喉气管炎病毒 DNA疫苗 免疫应管 

分 类 号：S858.315.3[农业科学—临床兽医学] S858.312.5[农业科学—兽医学]