3项肿瘤标志物在育龄女性体检者中的回顾性研究  

Retrospecive research on the expression of 3 kinds of tomor marker in childbearing age women

作　　者：陆其明 丁庆莉[2] 韩娟[2] 宋新爱[2] 任传路[2] 

机构地区：[1]苏州市吴江区黎里中心卫生院检验科,江苏苏州215212 [2]中国人民解放军第一〇〇医院检验科,江苏苏州215007

出　　处：《国际检验医学杂志》2013年第22期3011-3012,共2页International Journal of Laboratory Medicine

基　　金：南京军区科技公关课题资助项目(07M16)

摘　　要：目的回顾性研究CA125、CA19-9和CA72-4在月经期及Ⅰ期子宫内膜异位症(EM)育龄女性体检者中的表达。方法电化学发光法检测月经期(A组)、月经后(B组)及Ⅰ期EM(C组)各30名育龄女性体检者血清CA125、CA19-9和CA72-4的含量,并以健康对照组(D组)对照。结果 A、C两组的CA125和CA19-9明显高于D组,差异有统计学意义(P<0.05);B组的CA125和CA19-9也同时下降到接近健康对照水平,3组在阳性率表达方面也有相同趋势。而CA72-4在月经期的表达不高,在C组有46.7%的阳性率。结论月经期及Ⅰ期EM体检者3项肿瘤标志物存在不同程度的升高。Objective To retrospect ively study the expression of CA125,CA19-9 and CA72-4 in women of childbearing age in menstrual phase and phase I endometriosis（EM） during physical examination. Methods The expression of CA125, CA199 and CA72-4 were detected by electro-chemiluminescence immunoassay method for 30 women of childbearing age in menstrual phase （group A） ,after menstrual（group B） ,phase I endometriosis（group C）and healty contrast（group D）, respectively. Results The ex- pression levels of CA125 and CA19-9 in group A and C were significangtly higher than those of group D（P^O. 05） ,and those of group B decreased close to group D. The positive expression trends of group A, B, and C were the same. However, the expression levels of CA72-4 were low in group A, but high in group C（46.7 %）. Conclusion The expression levels of 3 kinds of tumor mark ers increased more or less in menstrual phase and phase I EM.

关 键 词：子宫内膜异位症 糖类抗原 月经周期 

分 类 号：R194.3[医药卫生—卫生事业管理]