中医药干预急性心肌梗死后心室重构的机理研究进展  

Mechanism research progress on intervention of TCM on ventricular remodeling after acute myocardial infarction

作　　者：董国菊[1] 

机构地区：[1]中国中医科学院西苑医院心血管科,北京100091

出　　处：《环球中医药》2013年第10期783-787,共5页Global Traditional Chinese Medicine

基　　金：国家自然科学基金青年基金(81001517);国家自然科学基金面上项目(81273929)

摘　　要：急性心肌梗死后心室重构直接影响了急性心肌梗死患者的预后,一直是心血管领域研究的焦点。中医药干预急性心肌梗死后心室重构有多靶点、多环节综合调控的优势,其作用机制涉及从血流动力学到神经内分泌系统,从心肌能量代谢到细胞凋亡等多个病理环节,展现了良好的应用前景。Ventricular remodeling （VR） after acute myocardial infarction （AMI） influences directly the prognosis of AMI patients, which has always been the research focus in the cardiovascular diseases. The mechanism of traditional Chinese medicine （TCM） on VR after AMI has the advantages of multi-targets and multi-channel, which involves several pathological parts from hemodynamic to neuroendocrine, from myocardial energy metabolism to cell apoptosis. The intervention of TCM shows a good application prospect.

关 键 词：中医药 急性心肌梗死 心室重构 机理研究 

分 类 号：R542.22[医药卫生—心血管疾病]