特立帕肽治疗绝经后妇女骨质疏松症的疗效观察  

Observation on the Effect of Teriparatide in the Treatment of Postmenopausal Women with Osteoporosis

作　　者：胡群 

机构地区：[1]江西新余新钢中心医院,江西新余338001

出　　处：《中国医学创新》2013年第32期19-20,共2页Medical Innovation of China

摘　　要：目的:探讨与观察特立帕肽治疗绝经后妇女骨质疏松症的疗效。方法:选取2010年9月-2012年12月于本院进行治疗的98例绝经后骨质疏松患者为研究对象,将其按照随机数字表法分为对照组和观察组各49例,对照组给予鲑鱼降钙素进行治疗,观察组给予特立帕肽进行治疗,然后将两组患者治疗前与治疗后12、24周的骨量情况及骨生化指标进行比较。结果:观察组治疗后12周与24周的骨量情况均优于对照组与本组治疗前,血清Ostase、ALP及BLAP均低于对照组与本组治疗前,比较差异均有统计学意义(P<0.05)。结论:特立帕肽治疗绝经后妇女骨质疏松症的疗效较好,可有效调控患者的骨生化指标。Objective：To investigate and observe the effect of teriparatide in the treatment of postmenopausal women with osteoporosis.Method：Ninety-eight postmenopausal women with osteoporosis in our hospital from September 2010 to December 2012 were selected as research objects,and they were randomly divided into the control group and the observation group according to the random number table method,49 cases in each group.The control group was given salmon calcitonin treatment,the observation group was given teriparatide treatment,then the bone mass state and bone biochemical indices of two groups before the treatment and at 12th and 24th week after the treatment were compared.Result：The bone mass state of observation group at 12th and 24th week after the treatment were better than those of control group and those before the treatment,and serum Ostase,ALP and BLAP were lower than those of control group too,the serum indexes were lower than those before the treatment,there were statistically significant differences（P〈0.05）. Conclusion：The effect of teriparatide in the treatment of postmenopausal women with osteoporosis is better,and it can effectively regulate the bone biochemical indices of patients.

关 键 词：特立帕肽 绝经后妇女 骨质疏松症 骨生化指标 疗效 

分 类 号：R580[医药卫生—内分泌]