补肾方对去卵巢大鼠下颌骨骨密度的影响  

The Influence of Mandible Bone Mineral Density of Ovariectomized Rats With Bu Shen Deloction

作　　者：肖明英[1] 王贻宁[2] 

机构地区：[1]湖北省中医药研究院,湖北武汉430074 [2]武汉大学口腔医院,湖北武汉430070

出　　处：《中国中医骨伤科杂志》2000年第6期19-20,共2页Chinese Journal of Traditional Medical Traumatology & Orthopedics

基　　金：湖北省卫生科研基金 !编号 2 0 0 0 0 5

摘　　要：目的 :探讨中药补肾方对去卵巢大鼠下颌骨骨密度的影响。方法 :将 2 4只雌性大鼠随机分为三组 ,每组 8只 ,即去卵巢给服中药组 ( BSD组 ) ,去卵巢给服生理盐水组 ( Model组 )和假手术给服生理盐水组( Sham组 ) ,观察 3个月后 ,测骨密度值。结果 :BSD组腰椎、股骨和下颌骨骨密度均高于 Model组 ( P<0 .0 5) ,而与 Sham组比较无差异 ( P>0 .0 5)。结论Objective:To study the influence of mandible bone mineral density of ovariectomized adult rats with Bu Shen Decoction(BSD).Methods:Twenty-four female rats were randomly divided into three groups (elght rats in each group):ovariectomized treated with BSD(BSD group),ovarietomized treated with normal saline(Model group) and sham surgery treated with normal saline(Sham group),measured the changes of bone mineral density(BMD) of the three groups after three months.Results:BMD of the lumbar spine、femur and mandible in BSD group is higher than that of Modle group(P<0.05).Compared with Sham group,there is no difference between Sham group and BSD group(P>0.05).Conclusion:The traditional Chinese herb BSD can prevent the osteporosis of ovarietomized rats mandible.

关 键 词：去卵巢大鼠 骨质疏松 下颌骨 骨密度 补肾方 

分 类 号：R271.917.5[医药卫生—中西医结合] R276.82[医药卫生—中医妇科学]