舒血宁注射液治疗冠心病左室舒张功能不全的临床疗效观察  

Shuxuening Injection in the Treatment of Coronary Heart Disease of Left Ventricular Diastolic Dysfunction Clinical Observation

作　　者：石玉娜[1] 张尧[1] 

机构地区：[1]邢台医学高等专科学校第二附属医院,河北邢台054002

出　　处：《中国医学创新》2013年第31期40-42,共3页Medical Innovation of China

摘　　要：目的:探讨观察舒血宁注射液治疗冠心病左室舒张功能不全的临床疗效、左室功能指标和安全性。方法:选取本院收治的冠心病左室舒张功能不全患者130例,按照随机编号法分成观察组和对照组各65例,两组患者均采取常规治疗,观察组在此基础上采取舒血宁注射液治疗,比较两组临床疗效、左室功能指标和安全性。结果:观察组治疗后舒张早期最大血流速、舒张晚期最大血流速、峰值速度比值与治疗前比较,差异有统计学意义(P<0.05)。对照组治疗后舒张早期最大血流速、舒张晚期最大血流速、峰值速度比值和多普勒超声心动图与治疗前比较,差异有统计学意义(P<0.05)。观察组治疗后舒张早期最大血流速、舒张晚期最大血流速、峰值速度比值与对照组治疗后比较,差异有统计学意义(P<0.05)。观察组总有效率86.15%明显高于对照组的53.85%,差异有统计学意义(P<0.05)。两组患者在本次试验中,均完成临床观察,未发生不良反应。结论:舒血宁注射液与常规方法联用可有效地改善冠心病合并左室舒张功能不全患者的左室功能,并且在改善心功能方面,效果显著,治疗效果比单一使用常规方法更好。Objective： To explore the concept of Shuxuening injection in the treatment of coronary heart disease of left ventricular diastolic dysfunction clinical efficacy and safety of left ventricular function parameters,Method Coronary heart disease in our hospital were selected and left ventricular diastolic dysfunction in patients with 130 cases, and they were randomly divided into the observation group and the control group, two groups were taken conventional treatment, the observation group was taken the Shuxuening injection treatment on the basis of the conventional treatment, the clinical curative effect, left ventricular function and safety of two groups were compared.Result： After treatment, the maximum flow velocity in early diastole, late diastolic maximum flow velocity, peak velocity ratio of the observation group compared with before treatment, the difference was statistically significant （ P〈0.05 ） .After treatment, the maximum flow velocity in early diastole, late diastolic maximum flow velocity, peak velocity ratio of the control group compared with before treatment, the difference was statistically significant （P〈0.05） .After treatment, the maximum flow velocity in early diastole, late diastolic maximum flow velocity, peak velocity ratio of the observation group compared with the control group, the difference was statistically significant （ P〈0.05 ） .The total effective of the observation group was 86.15%, it was was significantly higher than the control group （ 53.85% ）, the difference was statistically significant （ P〈0.05 ） .Two groups of patients in this study were completed clinical observation, no adverse reactions. Conclusion： Shuxuening injection combined with the conventional xnethod can effectively improve coronary heart disease and left ventricular diastolic dysfunction in patients with left ventricular function, and improve heart function, the effect is significant, the treatment effect is better than single-use conventional methods.

关 键 词：舒血宁注射液 冠心病 左室舒张功能不全 

分 类 号：R541.4[医药卫生—心血管疾病]