中药粉体改性技术的研究进展  

Advances in studies on modification technology of traditional Chinese medicine powders

作　　者：潘亚平[1,2] 张振海[1] 蒋艳荣[1] 贾晓斌[1] 

机构地区：[1]南京中医药大学附属江苏省中西医结合医院,国家中医药管理局中药释药系统重点研究室,江苏南京210028 [2]上海交通大学药学院,上海200240

出　　处：《中国中药杂志》2013年第22期3808-3813,共6页China Journal of Chinese Materia Medica

基　　金：江苏省中医药领军人才项目(81274088)

摘　　要：中药粉体大多表现出流动性差、吸湿性强、黏性大、润湿性差等不良物理性质,影响中药制剂的生产过程甚至疗效。准确表征中药粉体的物理性质并改变其不良特性成为提高中药制剂质量及推动中药现代化进程的关键。该文综述了中药粉体物理性质的评价方法和改性技术,为解决中药制剂研究和生产过程中存在的问题提供了思路和借鉴,从而实现中药制剂的质量控制标准化和剂型现代化。Most of the traditional Chinese medicine（TCM） powders showed bad physical properties, such as poor flowability, high hygroscopicity, agglomeration and poor wettability, which will affect the production process and even the efficacy of Chinese mate- ria medica preparations. The exact characterization of the physical properties of TCM powders and the reshaping technology become the key to improve the quality and efficacy of Chinese materia medica preparations and to promote the modernization process of TCM. This article summarizes the evaluation methods of the physical properties and the modification technology of TCM powders, in order to solve the problems existing in the research and production of Chinese materia medica preparations, and to achieve the quality control of drugs and modernization of dosage forms.

关 键 词：中药粉体 物理性质 改性技术 

分 类 号：TQ461[化学工程—制药化工]