医用316L不锈钢表面微结构的飞秒激光制备及血液相容性研究  

Microstructures prepared with a femtosecond laser on medical 316L stainless steel surface and the blood compatibility study

作　　者：吴勃[1,2] 周明[2,3] 李保家[2] 王云龙[2] 蔡兰[2] 

机构地区：[1]江苏大学机械工程学院,江苏镇江212013 [2]江苏大学材料科学与工程学院,光子制造科学技术中心江苏省重点实验室,江苏镇江212013 [3]清华大学磨擦学国家重点实验室,北京100084

出　　处：《功能材料》2013年第22期3291-3295,共5页Journal of Functional Materials

基　　金：国家重点基础研究发展计划(973计划)资助项目(2011CB013000);国家自然科学基金资助项目(50975128;50975129);江苏省光子制造科学与技术重点实验室开放基金资助项目(GZ200714)

摘　　要：利用飞秒激光在316L不锈钢表面诱导制备血液相容性微结构,并从微结构的润湿性角度分析血液相容性改善的机理。随着激光能量密度的增加,在样品表面分别制备了单一的亚微米级典型激光诱导周期性波纹(LIPSS),以及两种双尺度结构,即覆盖了LIPSS的微米级波纹结构和锥状钉结构。硅烷化后的微结构样品表观接触角都超过150°,达到了超疏水性能要求,并且随着所采用激光能量密度的增强而增大,尤其是锥状钉双尺度结构的接触角达到了163.8°。采用了3种常规评价方法对微结构表面的血液相容性进行了评价,结果表明微结构表面的血液相容性显著优于光滑表面,且随着表面的表观接触角的增大而改善。Microstructures with a good blood compatibility on the surface of stainless steel were prepared by using a femtosecond laser.The mechanism of the blood compatibility improvement was analyzed from the wet-tability of the microstructure perspective.With laser fluence increasing,we fabricated single typical laser-in-duced periodic surface structures （LIPSS）on the submicron scale and double-scale structure：periodic ripples and periodic cone-shaped spikes on the micron scale,both covered with LIPSS.After silanized,the apparent contact angles of these microstructures become larger than 150°,which meets the superhydrophobic perform-ance requirements.With the laser fluence increasing,the apparent contact angles increase,and especially the contact angle of the cone-shaped double-scale structure reaches as high as 163.8°.The blood compatibility of the microstructures was evaluated with 3 conventional evaluation methods.The results show that the blood com-patibility of the microstructures was significantly better than that of the polished surface,and that with the con-tact angles of the surface increasing,the blood compatibility can be further improved.

关 键 词：超快光学 飞秒激光 表面微结构 血液相容性 医用不锈钢 

分 类 号：TN249[电子电信—物理电子学] R318.08[医药卫生—生物医学工程]