瑞芬太尼递减停药法对术后痛觉过敏的影响  

Effect of diminishing withdrawal of remifentanil on postoperative hyperalgesia

作　　者：许丽明[1] 王宏梗[1] 

机构地区：[1]福建医科大学附属第二医院麻醉科,福建泉州362000

出　　处：《中国校医》2013年第11期845-847,共3页Chinese Journal of School Doctor

摘　　要：目的观察瑞芬太尼递减停药法对术后痛觉过敏的影响。方法全麻择期腹腔镜下胃癌根治术男性患者40例,ASA分级I^II级,随机分为2组,瑞芬太尼递减停药组(G组)和瑞芬太尼恒速给药组(C组),每组20例;观察2组术后发生痛觉过敏的程度、追加舒芬太尼的剂量,对患者自主呼吸、意识恢复和拔管时间的影响,以及不良反应如呼吸抑制的发生率。结果 2组拔管时间差异无统计学意义(P>0.05),2组术后VAS评分差异有统计学意义(P<0.05)。结论瑞芬太尼递减停药法可减少术后痛觉过敏的发生。Objective To evaluate the effect of diminishing withdrawal of remifentanil on postoperative hyperalgesia. Methods Totally 40 patients who received the elective surgery, laparoscopic radical resection for gastric cancer by general anesthesia （ASA levels I-II） were divided into 2 groups randomly： Group G （diminishing withdrawal of remifentanil, 20 cases） and Group C （remifentaniL infuse with constant speed, 20 cases）. The levels of hyperalgesia after the operation and the proportion for the supplementary dose of sulfentanil, its influence on spontaneous breathing, recovery of , extubation time, and its adverse reaction, such as the incidence of respiratory depression were observed. Results Two groups showed no significant difference in extubation time （P 〉 0.05）. However, two groups showed a significant difference in postoperative VAS scores （ P 〈 0.05 ）. Conclusions The method of diminishing withdrawal of remifentanil can reduce the incidence of postoperative hyperalgesia.

关 键 词：瑞芬太尼 痛觉过敏 用药计划表 

分 类 号：R614[医药卫生—麻醉学]