EMS患者治疗前后血清IL-6、IL-18、SOD和VEGF测定的临床意义  

Clinical Significance of Measurment the Changes on Serum IL-6,IL-18,SOD and VEGF Levels Before and After Treatment in Patients with Endometriosis

作　　者：张春艳[1] 徐金霞[1] 

机构地区：[1]江苏省淮安市妇幼保健院,223001

出　　处：《放射免疫学杂志》2013年第6期715-717,共3页Journal of Radioimmanology

摘　　要：目的:探讨了子宫内膜异位症(EMS)患者治疗前后血清IL-6、IL-18、SOD和VEGF水平的变化及临床意义。方法:应用放射免疫分析和酶联法对33例EMS患者进行了血清IL-6、IL-18、SOD和VEGF检测,并与35名正常人作比较。结果:EMS患者在治疗前血清IL-6、IL-18、SOD和VEGF水平均非常显著地高于正常人组(P<0.01),经中西医结合治疗3个月后则与正常人组比较无显著性差异(P>0.05)。结论:EMS的发生、发展与血清IL-6、IL-18、SOD和VEGF水平密切相关。Objective To explore the clinical significance of changes on serum IL-6, IL-18, SOD and VEGF levels both before and after treatment in patients with endometdosis. MethOdS Serum IL-6, IL-18, SOD（with RIA） serum VEGF（with ELISA） levels were determined in 33 patients with endometriosis both before and after treatment and compared with 35 normal healthy persons as control. Results Before treatment the serum IL-6, IL-18, SOD and VEGF levels in the patients showed obviously higher than those in controls （ P 〈 0.01 ）, after 3 months treatment the levels expressed no significant difference from those in controls （ P 〉 0. 05 ）. Conclusion Development and progress of endometriosis closely related to the serum levels of IL-6, IL-18, SOD and VEGF.

关 键 词：子宫内膜异位症 白细胞介素-6 白细胞介素-18超氧化物歧化酶血管内皮生长因子 

分 类 号：R581.1[医药卫生—内分泌]