安宫牛黄丸中牛黄的质量分析和研究对策  

Type and Quality Study of Calculus Bovis in Commercial Angong Niuhuang Pills

作　　者：夏晶[1] 曹帅[1] 杨新华[1] 钟吉强[1] 季申[1] 

机构地区：[1]上海市食品药品检验所,上海201203

出　　处：《中国药学杂志》2013年第23期2048-2055,共8页Chinese Pharmaceutical Journal

基　　金：中药质量标准研究和信息化体系平台建设资助项目(2009ZX09308-004):科技部重大新药创制课题;<中国药典>2015年版药典标准专项研究"含牛黄类中成药中牛黄的检测方法研究"资助项目

摘　　要：目的对安宫牛黄丸中牛黄的质量进行研究和分析,为进一步建立专属合理的质量控制方法、规范和健全其生产、保障质量提供依据。方法对安宫牛黄丸中牛黄的主要专属性成分和有效成分等采用多种手段及指标进行分析,比较及研究,合理评价安宫牛黄丸中牛黄的质量现状。结果结果显示,安宫牛黄丸中牛黄在原料质量等方面的问题,提出了解决的对策和建议,为其他含牛黄制剂提供了借鉴。结论重视安宫牛黄丸中牛黄的质量是保证该药疗效和安全的关键因素。OBJECTIVE To study the type and quality of Calculus Bovis in commercial Angong Niuhuang Pills （traditional Chi- nese medicines） and provide technical support to fight against counterfeits. METHODS Specific and effective components of Calcu- lus Boris were studied. The type of Calculus Bovis in commercial Angong Niuhuang Pills was identified according to the differences in components and content. RESULTS Illegal use of artificial Calculus Bovis or bilirubin was found to be a serious problem. The type and quality of Calculus Bovis in Angong Niuhuang Pills differed greatly. CONCLUSION Calculus Bovis adulteration in Angong Ni- uhuang Pills is a very serious problem which needs urgent supervision and regulation to assure safe medication,

关 键 词：安宫牛黄丸 牛黄 质量 

分 类 号：R917[医药卫生—药物分析学]