难治性狼疮性肾炎治疗的现状与进展  

Recent Advances of Treatment for Refractory Lupus Nephritis

作　　者：魏玉翠[1] 梁兰青[2] 

机构地区：[1]新疆医科大学,乌鲁木齐830054 [2]中国人民解放军兰州军区乌鲁木齐总医院肾脏病科,乌鲁木齐830000

出　　处：《医学综述》2013年第22期4118-4122,共5页Medical Recapitulate

摘　　要：狼疮性肾炎(LN)是系统性红斑狼疮(SLE)最常见的并发症之一,也是SLE预后的关键因素。目前LN的治疗仍以糖皮质激素和免疫抑制剂为基础。近年来,尽管LN的治疗明显提高,但仍有部分患者对常规治疗无效或反应不佳,进展到终末期肾衰竭,目前LN的治疗仍然是一个挑战。该文就难治性LN治疗的现状与进展进行综述。Lupus nephritis（ LN）is one＂ of the common ＂complications of systemic lupus erythematosus （ SLE）, and also one of the key factors of prognosis for SLE. At present, the treatment of LN is still based on glucoeorticoid and immunosuppressant. In recent years, despite improvements in the management of LN, a sig- nificant number of the patients do not respond to immunosuppressive therapy and develop into end-stage renal failure, and its treatment remains a challenge. Here is to make a review of the current status and progress of treatment of refractory LN.

关 键 词：系统性红斑狼疮 狼疮性肾炎 难治性 治疗 

分 类 号：R692[医药卫生—泌尿科学]